Cat.No.:	IL18-742H
Product Overview:	Recombinant human IL18 was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. MW: 18.3 kDa.
Description:	IL18 is an activator of NK cells and a co-inducer of Th1 cytokines. IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon.
Source:	E. coli
Species:	Human
Tag:	N/A
Form:	Liquid. In Phosphate buffer saline (pH 7.4).
Molecular Mass:	18.3 kDa (158aa), confirmed by MALDI-TOF.
AA Sequence:	MYFGKLESKL SVIRNLNDQV LFIDQGNRPL FEDMTDSDCR DNAPRTIFII SMYKDSQPRG MAVTISVKCE KISTLSCENK IISFKEMNPP DNIKDTKSDI IFFQRSVPGH DNKMQFESSS YEGYFLACEK ERDLFKLILK KEDELGDRSI MFTVQNED
Endotoxin:	< 1.0 eu per 1 ug of protein (determined by lal
Purity:	>95% by SDS - PAGE
Applications:	SDS-PAGE
Storage:	Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration:	1 mg/ml (determined by Bradford assay)

Gene Name:	IL18 interleukin 18 (interferon-gamma-inducing factor) [ Homo sapiens ]
Official Symbol:	IL18
Synonyms:	IL18; interleukin 18 (interferon-gamma-inducing factor); interleukin-18; IGIF; IL 1g; IL 18; IL1F4; IL-1 gamma; iboctadekin; interleukin-1 gamma; IFN-gamma-inducing factor; IL-18; IL-1g; MGC12320;
Gene ID:	3606
mRNA Refseq:	NM_001243211
Protein Refseq:	NP_001230140
MIM:	600953
UniProt ID:	Q14116
Chromosome Location:	11q22.2-q22.3
Pathway:	African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cellular roles of Anthrax toxin, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem;
Function:	cytokine activity; cytokine activity;

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