Recombinant Mouse Leptin
Cat.No. : | Lep-6933M |
Product Overview : | Recombinant mouse Lep was overexpressed as insoluble protein aggregate in E. coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. MW: 16 kDa. |
- Specification
- Gene Information
- Related Products
Description : | Lep is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. |
Source : | E. coli |
Species : | Mouse |
Tag : | N/A |
Form : | Liquid. In Phosphate buffered saline (pH 7.4). |
Molecular Mass : | 16 kDa (147 aa), confirmed by MALDI-TOF. |
Protein length : | 1-250aa |
AA Sequence : | MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC |
Purity : | >95% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | Lep leptin [ Mus musculus ] |
Official Symbol : | Lep |
Synonyms : | LEP; leptin; obesity factor; ob; obese; |
Gene ID : | 16846 |
mRNA Refseq : | NM_008493 |
Protein Refseq : | NP_032519 |
Pathway : | Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; |
Function : | growth factor activity; hormone activity; peptide hormone receptor binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
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LEP-203R | Recombinant Rat LEP Protein | +Inquiry |
LEP-2725R | Recombinant Rhesus monkey LEP Protein, His-tagged | +Inquiry |
LEP-1088P | Recombinant Pig LEP Protein, His-tagged | +Inquiry |
LEP-3626H | Recombinant Human Leptin | +Inquiry |
◆ Native Protein | ||
LEP-27641TH | Native Human LEP | +Inquiry |
◆ Lysates | ||
LEP-4773HCL | Recombinant Human LEP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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