Recombinant Human SMUG1, His-tagged
Cat.No. : | SMUG1-7066H |
Product Overview : | Recombinant human SMUG1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | Single-strand-selective monofunctional uracil-DNA glycosylase, also known as SMUG1, is a enzyme responsible for recognizing base lesions in the genome and initiating base excision DNA repair. This protein acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA and has a preference for single-stranded DNA substrates. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl,30% glycerol, 1mM DTT |
Molecular Mass : | 32.3 kDa (293aa) |
Protein length : | 1-270aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMPQAFLL GSIHEPAGAL MEPQPCPGSL AESFLEEELR LNAELSQLQF SEPVGIIYNP VEYAWEPHRN YVTRYCQGPK EVLFLGMNPG PFGMAQTGVP FGEVSMVRDW LGIVGPVLTP PQEHPKRPVL GLECPQSEVS GARFWGFFRN LCGQPEVFFH HCFVHNLCPL LFLAPSGRNL TPAELPAKQR EQLLGICDAA LCRQVQLLGV RLVVGVGRLA EQRARRALAG LMPEVQVEGL LHPSPRNPQA NKGWEAVAKE RLNELGLLPL LLK |
Purity : | >95% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml |
Gene Name : | SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 [ Homo sapiens ] |
Official Symbol : | SMUG1 |
Synonyms : | SMUG1; single-strand-selective monofunctional uracil-DNA glycosylase 1; single-strand selective monofunctional uracil DNA glycosylase; FDG; HMUDG; UNG3; MGC104370; |
Gene ID : | 23583 |
mRNA Refseq : | NM_001243787 |
Protein Refseq : | NP_001230716 |
MIM : | 607753 |
UniProt ID : | Q53HV7 |
Chromosome Location : | 12q13.11-q13.3 |
Pathway : | Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; Cleavage of the damaged pyrimidine, organism-specific biosystem; DNA Repair, organism-specific biosystem; |
Function : | DNA N-glycosylase activity; DNA binding; hydrolase activity, acting on glycosyl bonds; protein binding; single-strand selective uracil DNA N-glycosylase activity; uracil DNA N-glycosylase activity; |
Products Types
◆ Recombinant Protein | ||
SMUG1-4168R | Recombinant Rhesus Macaque SMUG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SMUG1-8504M | Recombinant Mouse SMUG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Smug1-5983M | Recombinant Mouse Smug1 Protein, Myc/DDK-tagged | +Inquiry |
SMUG1-5288R | Recombinant Rat SMUG1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SMUG1-2826H | Recombinant Human SMUG1, GST-tagged | +Inquiry |
◆ Lysates | ||
SMUG1-1648HCL | Recombinant Human SMUG1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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