"NKX3-1" Related Products

Recombinant Human NKX3-1, His-tagged

Cat.No.: NKX3-1-7100H
Product Overview: Recombinant human NKX3-1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Description: NKX3-1 is a homeobox-containing transcription factor, which binds preferentially the consensus sequence 5"-TAAGT[AG]-3" and can behave as a transcriptional repressor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of NKX3-1 is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2M UREA, 10% glycerol
Molecular Mass: 28.7kDa (257aa)
Protein length: 1-234aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMLRVPEP RPGEAKAEGA APPTPSKPLT SFLIQDILRD GAQRQGGRTS SQRQRDPEPE PEPEPEGGRSRAGAQNDQLS TGPRAAPEEA ETLAETEPER HLGSYLLDSE NTSGALPRLP QTPKQPQKRS RAAFSHTQVI ELERKFSHQK YLSAPERAHL AKNLKLTETQ VKIWFQNRRY KTKRKQLSSE LGDLEKHSSL PALKEEAFSR ASLVSVYNSY PYYPYLYCVG SWSPAFW
Purity: >85% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml
Gene Name: NKX3-1 NK3 homeobox 1 [ Homo sapiens ]
Official Symbol: NKX3-1
Synonyms: NKX3-1; NK3 homeobox 1; NK homeobox (Drosophila), family 3, A , NK3 transcription factor related, locus 1 (Drosophila) , NKX3A; homeobox protein Nkx-3.1; BAPX2; NKX3.1; NK homeobox, family 3, A; homeobox protein NK-3 homolog A; NK3 transcription factor homolog A; NK3 transcription factor related, locus 1; NKX3; NKX3A;
Gene ID: 4824
mRNA Refseq: NM_001256339
Protein Refseq: NP_001243268
MIM: 602041
UniProt ID: Q99801
Chromosome Location: 8p21.2
Pathway: Coregulation of Androgen receptor activity, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; Prostate cancer, organism-specific biosystem; Prostate cancer, conserved biosystem; SIDS Susceptibility Pathways, organism-specific biosystem;
Function: androgen receptor activity; core promoter binding; contributes_to cysteine-type endopeptidase activator activity involved in apoptotic process; estrogen receptor activity; estrogen receptor binding; histone deacetylase binding; protein binding; protein binding transcription factor activity; protein kinase activator activity; protein self-association; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding; transcription regulatory region sequence-specific DNA binding;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.