Recombinant Human KRT19 Protein, His tagged
Cat.No. : | KRT19-7239H |
Product Overview : | Recombinant Human KRT19 Protein with His tag was expressed in E. coli. |
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- Specification
- Gene Information
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Description : | The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Molecular Mass : | The protein has a calculated MW of 47 kDa. |
AA Sequence : | MGSSHHHHHHSSGLVPRGSHMGSMT SYSYRQSSATSSFGGLGGGSVRFGP GVAFRAPSIHGGSGGRGVSVSSARF VSSSSSGAYGGGYGGVLTASDGLLA GNEKLTMQNLNDRLASYLDKVRALE AANGELEVKIRDWYQKQGPGPSRDY SHYYTTIQDLRDKILGATIENSRIV LQIDNARLAADDFRTKFETEQALRM SVEADINGLRRVLDELTLARTDLEM QIEGLKEELAYLKKNHEEEISTLRG QVGGQVSVEVDSAPGTDLAKILSDM RSQYEVMAEQNRKDAEAWFTSRTEE LNREVAGHTEQLQMSRSEVTDLRRT LQGLEIELQSQLSMKAALEDTLAET EARFGAQLAHIQALISGIEAQLGDV RADSERQNQEYQRLMDIKSRLEQEI ATYRSLLEGQEDHYNNLSASKVL |
Endotoxin : | < 1 EU/μg by LAL |
Purity : | > 90% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 1 mg/mL by BCA |
Storage Buffer : | Sterile PBS, pH 7.4 |
Publication : |
Pancreatic cancer cells assemble a CXCL12-keratin 19 coating to resist immunotherapy (2020)
Carcinomas assemble a filamentous CXCL12–keratin-19 coating that suppresses T cell–mediated immune attack (2022)
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Gene Name : | KRT19 keratin 19 [ Homo sapiens ] |
Official Symbol : | KRT19 |
Synonyms : | KRT19; keratin 19; keratin, type I cytoskeletal 19; 40 kDa keratin intermediate filament; CK19; cytokeratin 19; K1CS; K19; keratin; type I cytoskeletal 19; type I; 40 kd; MGC15366; CK-19; keratin-19; cytokeratin-19; keratin, type I, 40-kd; 40-kDa keratin intermediate filament; |
Gene ID : | 3880 |
mRNA Refseq : | NM_002276 |
Protein Refseq : | NP_002267 |
MIM : | 148020 |
UniProt ID : | P08727 |
Products Types
◆ Recombinant Protein | ||
KRT19-2605H | Recombinant Human KRT19 protein(81-400 aa), N-MBP & C-His-tagged | +Inquiry |
KRT19-2604H | Recombinant Human KRT19 protein(81-400 aa), C-His-tagged | +Inquiry |
KRT19-001H | Recombinant Human KRT19 Protein, His-tagged | +Inquiry |
KRT19-4865H | Recombinant Human KRT19 Protein, GST-tagged | +Inquiry |
KRT19-0025H | Recombinant Human KRT19 Protein | +Inquiry |
◆ Native Protein | ||
KRT19-382H | Native Human KRT19 | +Inquiry |
KRT19-40H | Native Human KRT19 protein | +Inquiry |
KRT19-5H | Native Human CK19 | +Inquiry |
◆ Lysates | ||
KRT19-4875HCL | Recombinant Human KRT19 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, there are ongoing clinical trials exploring the use of KRT19 as a biomarker and its potential as a therapeutic target in cancer treatment.
Yes, KRT19 can also be used as a biomarker in other diseases, such as liver diseases and rheumatoid arthritis.
Some targeted therapies are being developed that specifically target cancer cells with high KRT19 expression.
Yes, KRT19 expression levels can provide information about the prognosis of cancer patients, helping in treatment planning.
KRT19 protein can be detected using various laboratory techniques, including immunohistochemistry, ELISA, and PCR.
Customer Reviews (3)
Write a reviewSuch support helps researchers overcome challenges and obtain reliable results.
This flexibility allows researchers to focus on specific aspects of KRT19 protein functionality, regulation, or disease associations, enhancing the relevance and applicability of their work.
Manufacturers might offer customization options, such as different variants or modifications of the KRT19 protein, to cater to specific research requirements.
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