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Recombinant Human RGS5, His-tagged

Cat.No. : RGS5-3617H
Product Overview : Recombinanthuman RGS5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
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Cat. No. : RGS5-3617H
Description : RGS5, also known as regulator of G-protein signaling 5, binds directly to activated G alpha subunits and act as GTPase-activating proteins(GAPs) to attenuate and/or modulate hormone and neurotransmitter receptor-initiated signaling by both G alpha-GTP and G beta gamma. Vascular endothelial cells express the RGS protein RGS5, where it correlates with capillary morphogenesis, thus rendering it a candidate gene involved in capillary growth, angiogenesis, and also potentially the pathophysiology of stroke.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
Molecular Weight : 23.5 kDa (205aa), confirmed by MALDI-TOF
Purity : > 90% by SDS - PAGE
Concentration : 0.5 mg/ml (determined by Bradford assay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MGSHMCKGLA ALPHSCLERA KEIKIKLGIL LQKPDSVGDL VIPYNEKPEK PAKTQKTSLD EALQWRDSLDKLLQNNYGLA SFKSFLKSEF SEENLEFWIA CEDYKKIKSP AKMAEKAKQI YEEFIQTEAP KEVNIDHFTK DITMKNLVEP SLSSFDMAQKRIHALMEKDS LPRFVRSEFY QELIK
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : RGS5 regulator of G-protein signaling 5 [ Homo sapiens ]
Official Symbol : RGS5
Synonyms : RGS5; MST092; MST106; MST129; MSTP032; MSTP092; regulator of G-protein signaling 5; OTTHUMP00000032361; OTTHUMP00000232302; MSTP106; MSTP129
Gene ID : 8490
mRNA Refseq : NM_001195303
Protein Refseq : NP_001182232
MIM : 603276
UniProt ID : O15539
Chromosome Location : 1q23.1
Function : GTPase activator activity; signal transducer activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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