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Recombinant Human RND1, His-tagged

Cat.No. : RND1-3600H
Product Overview : Recombinant human RND1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography (1-200 aa).
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Cat. No. : RND1-3600H
Description : RND1, also known as Rho 6, is Rho-related GTPases form a distinct branch of the Rho family, since they differ from other Rho proteins in size, charge, and biochemical properties. It appears to be constitutively in the activated GTP-bound form and acts as negative regulators of actin assembly and of cell adhesion. It contributes to regulating the organization of the actin cytoskeleton in response to extracellular growth factors.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol 0.1M NaCl,1mM DTT
Molecular Weight : 24.5 kDa (220aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
Purity : > 95% by SDS - PAGE
Concentration : 0.5 mg/ml (determined by Bradford assay)
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MKERRAPQPV VARCKLVLVG DVQCGKTAML QVLAKDCYPE TYVPTVFENY TACLETEEQR VELSLWDTSG SPYYDNVRPL CYSDSDAVLL CFDISRPETV DSALKKWRTE ILDYCPSTRV LLIGCKTDLR TDLSTLMELS HQKQAPISYE QGCAIAKQLG AEIYLEGSAF TSEKSIHSIF RTASMLCLNK PSPLPQKSPV
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : RND1 Rho family GTPase 1 [ Homo sapiens ]
Official Symbol : RND1
Synonyms : ARHS; RHO6; RHOS; FLJ42294; RND1; rho-related GTP-binding protein Rho6; GTP-binding protein; ras homolog gene family, member; Rho family GTPase 1; Rho6; Rnd1
Gene ID : 27289
mRNA Refseq : NM_014470
Protein Refseq : NP_055285
MIM : 609038
UniProt ID : Q92730
Chromosome Location : 12q12
Function : GTP binding; GTPase activity; nucleotide binding; protein binding; receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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