"Tnfsf11" Related Products

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Recombinant Mouse TNFSF11

Cat. No.: Tnfsf11-192M
Product Overview: Recombinant Mouse TNFSF11 was expressed in Yeast.
Description: RANKL binds to tnfrsf11b/opg and to tnfrsf11a/rank. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive t-cell proliferation. May be an important regulator of interactions between t-cells and dendritic cells and may play a role in the regulation of the t-cell-dependent immune response. sRANKL may also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
Source: Yeast
MolecularMass: 19.8 kDa
Formulation: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purity: >95% as determined by SDS­PAGE analysis.
ProteinSequence: FSGAPAMMEG SWLDVAQRGK PEAQPFAHLT INAASIPSGS HKVTLSSWYH DRGWAKISNM TLSNGKLRVN QDGFYYLYAN ICFRHHETSG SVPTDYLQLM VYVVKTSIKI PSSHNLMKGG STKNWSGNSE FHFYSINVGG FFKLRAGEEI SIQVSNPSLL DPDQDATYFG AFKVQDID (178)
Purification: Ion-exchange chromatography
Storage: Stable for up to twelve months from date of receipt at -20 oC. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20 oC. Avoid repeated freeze/thaw cycles.
OfficialSymbol: Tnfsf11
Gene Name: Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 [ Mus musculus ]
Synonyms: Tnfsf11; tumor necrosis factor (ligand) superfamily, member 11; ODF; OPG; OPGL; RANKL; Ly109l; Trance; OPG ligand; osteoprotegerin ligand; osteoclast differentiation factor; receptor activator of NF-kappaB ligand; tumor necrosis factor-related activation-induced cytokine; Ly109l
Gene ID: 21943
mRNA Refseq: NM_011613
Protein Refseq: NP_035743
UniProt ID: O35235
Chromosome Location: 14 D3
Pathway: Cytokine-cytokine receptor interaction
Function: cytokine activity; protein binding; receptor activity; tumor necrosis factor receptor binding

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