Recombinant Human FXYD5, His-tagged

• Cat.No.: FXYD5-7524H
• Product Overview: Recombinant human FXYD5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Antigen Description: FXYD domain-containing ion transport regulator 5, also known as FXYD5, is a cancer-associated cell membrane glycoprotein which belongs to the FXYD family. FXYD5 is involved in down-regulation of E-cadherin, which plays important roles in tumor development and metastasis. It is present in spleen, lung, skeletal muscle, and testis tissue, and maps to human chromosome 19q13.2.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 16.1 kDa (147aa) confirmed by MALDI-TOF(Molecular size on SDS-PAGE will appear higher)
• Protein length: 22-145aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSQTLKDTT SSSSADSTIM DIQVPTRAPD AVYTELQPTS PTPTWPADET PQPQTQTQQL EGTDGPLVTD PETHKSTKAA HPTDDTTTLS ERPSPSTDVQ TDPQTLKPSG FHEDDPFFYD EHTLRKR
• Purity: >95% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: FXYD5 FXYD domain containing ion transport regulator 5 [ Homo sapiens ]
• Official Symbol: FXYD5
• Synonyms: FXYD5; FXYD domain containing ion transport regulator 5; FXYD domain-containing ion transport regulator 5; dysadherin; OIT2; keratinocytes associated transmembrane protein 1; RIC; IWU1; KCT1; DYSAD; HSPC113; PRO6241
• Gene ID: 53827
• mRNA Refseq: NM_001164605
• Protein Refseq: NP_001158077
• MIM: 606669
• UniProt ID: Q96DB9
• Chromosome Location: 19q13.12
• Function: actin binding; cadherin binding; ion channel activity