Recombinant Human IGJ, His-tagged

• Cat.No.: IGJ-7595H
• Product Overview: Recombinant human IGJ protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Antigen Description: Immunoglobulin J chain, also known as IGJ, serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also helps to bind these immunoglobulins to secretory component.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 18.0 kDa (160aa) confirmed by MALDI-TOF
• Protein length: 23-159aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSQEDERIV LVDNKCKCAR ITSRIIRSSE DPNEDIVERN IRIIVPLNNR ENISDPTSPL RTRFVYHLSD LCKKCDPTEV ELDNQIVTAT QSNICDEDSA TETCYTYDRN KCYTAVVPLV YGGETKMVET ALTPDACYPD
• Purity: >85% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: IGJ immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides [ Homo sapiens ]
• Official Symbol: IGJ
• Synonyms: IGJ; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; immunoglobulin J chain; IGCJ; IgJ chain; JCH
• Gene ID: 3512
• mRNA Refseq: NM_144646
• Protein Refseq: NP_653247
• MIM: 147790
• UniProt ID: P01591
• Chromosome Location: 4q21
• Function: antigen binding