Recombinant Human CD72 molecule

• Cat.No.: CD72-4268H
• Product Overview: CD72 Human Recombinant (aa 1-98) expressed in E.coli, shows a 38 kDa band on SDS-PAGE. The CD72 is purified by proprietary chromatographic techniques.

Specification

• Cat. No.: CD72-4268H
• Description: CD72 antigen is a member of the type II integral membrane glycoproteins which includes other related cell surface moleculaes such as the asialoglycoprotein receptors, CD23 and the Kupffer cell recpeotr. The function of CD72 is unknown but the exposure of B cells to CD72 antibodies activates a variety of signaling pathways and can induce MHC class II expression and B cell proliferation. CD72 antigen is expressed on all cells of B cell lineage with the exception of plasma cells and weakly on human tissue macrophages.
• Source: Human
• Host: Escherichia Coli.
• Form: CD72 at 100µg/ml in 50mM Tris-HCl, pH7.5, 10mM L-glutathione (reduced).
• Physical Appearance: Sterile Filtered clear solution.
• Storage: Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.

Gene Information

• Gene Name: CD72 CD72 molecule [ Homo sapiens ]
• Official Symbol: CD72
• Synonyms: CD72; CD72 molecule; LYB2; CD72b; B-cell differentiation antigen CD72; lyb-2; CD72 antigen; OTTHUMP00000021342; Lyb-2
• Gene ID: 971
• mRNA Refseq: NM_001782
• Protein Refseq: NP_001773
• MIM: 107272
• UniProt ID: P21854
• Chromosome Location: 9p13.3
• Pathway: Axon guidance; B Cell Receptor Signaling Pathway; B cell receptor signaling pathway; BCR signaling pathway; Sema4D in semaphorin signaling; Semaphorin interactions
• Function: binding; protein binding; receptor binding; sugar binding; transmembrane receptor activity