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Recombinant Human CD72 molecule

Cat. No.: CD72-4268H
Product Overview: CD72 Human Recombinant (aa 1-98) expressed in E.coli, shows a 38 kDa band on SDS-PAGE. The CD72 is purified by proprietary chromatographic techniques.
Description: CD72 antigen is a member of the type II integral membrane glycoproteins which includes other related cell surface moleculaes such as the asialoglycoprotein receptors, CD23 and the Kupffer cell recpeotr. The function of CD72 is unknown but the exposure of B cells to CD72 antibodies activates a variety of signaling pathways and can induce MHC class II expression and B cell proliferation. CD72 antigen is expressed on all cells of B cell lineage with the exception of plasma cells and weakly on human tissue macrophages.
Source: Human
Host: Escherichia Coli.
Form: CD72 at 100µg/ml in 50mM Tris-HCl, pH7.5, 10mM L-glutathione (reduced).
Physical Appearance: Sterile Filtered clear solution.
Storage: Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.
Gene Name: CD72 CD72 molecule [ Homo sapiens ]
Official Symbol: CD72
Synonyms: CD72; CD72 molecule; LYB2; CD72b; B-cell differentiation antigen CD72; lyb-2; CD72 antigen; OTTHUMP00000021342; Lyb-2
Gene ID: 971
mRNA Refseq: NM_001782
Protein Refseq: NP_001773
MIM: 107272
UniProt ID: P21854
Chromosome Location: 9p13.3
Pathway: Axon guidance; B Cell Receptor Signaling Pathway; B cell receptor signaling pathway; BCR signaling pathway; Sema4D in semaphorin signaling; Semaphorin interactions
Function: binding; protein binding; receptor binding; sugar binding; transmembrane receptor activity

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