|Cat. No. :
|Product Overview :
||NY-ESO-1 Human Recombinant full length protein expressed in E.coli, shows a 49 kDa SDS-PAGE (including GST tag). The NY-ESO-1 is purified by proprietary chromatographic techniques.
||NY-ESO-1, a member of the CT (cancer/testis) family, is a tumor-specific shared antigen with distinctive immunogenicity. NY-ESO-1 is expressed in testis and ovary and in a wide variety of cancers. It is also detected in uterine myometrium. The expression is from 18 weeks until birth in human fetal testis. Furthermore, in the adult testis, NY-ESO-1 is strongly expressed in spermatogonia and in primary spermatocytes, but not in post-meiotic cells or in testicular somatic cells (at protein level). The molecular basis of T cell-mediated antitumor immunity has been elucidated by the identification of a number of tumor antigens recognized by CD8+ T cells. Among these antigens, NY-ESO-1 is of particular interest because both the cytotoxic T lymphocyte and antibody have been shown to react with this antigen.
||NY-ESO-1 at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
|Physical Appearance :
||Sterile Filtered clear solution.
||Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.