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Recombinant Human FETUB protein, His-tagged

Cat.No. : FETUB-3788H
Product Overview : Recombinant Human FETUB (Cys16-Pro382) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).
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  • Gene Information
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Description : Fetuin-B (FETUB), a second member of the fetuin family in mammals, is also known as Fetuin-like protein IRL685, 16G2 and Gugu, which is expressed in liver and testis and contains 2 cystatin fetuin-B-type domains. FETUB is a protease inhibitor required for egg fertilization. FETUB is also required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). As a liver-derived plasma protein, FETUB is essential for fertilization.
Source : HEK293
Species : Human
Tag : His
Predicted N Terminal : Cys16
Form : Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 42.4 kDa. The protein migrates as 48-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein length : Cys16-Pro382
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >95% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : FETUB
Official Symbol : FETUB
Synonyms : FETUB; fetuin B; fetuin-B; fetuin-like protein IRL685; 16G2; Gugu; IRL685
Gene ID : 26998
mRNA Refseq : NM_014375
Protein Refseq : NP_055190
MIM : 605954
UniProt ID : Q9UGM5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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