Recombinant Human FGF2 protein
Cat.No. : | FGF2-590H |
Product Overview : | Recombinant Human FGF2 protein (Pro143-Ser288) carries no tag and was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | FGF basic is a member of the FGF family of at least 23 related mitogenic proteins which show 35-60% amino acid conservation. FGF acidic and basic, unlike the other members of the family, lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway. FGF basic has been isolated from a number of sources, including neural tissue, pituitary, adrenal cortex, corpus luteum, and placenta. This factor contains four cysteine residues, but reduced FGF basic retains full biological activity, indicating that disulfide bonds are not required for this activity. bFGF is a critical component of human embryonic stem cell culture medium; the growth factor is necessary for the cells to remain in an undifferentiated state, although the mechanisms by which it does this are poorly defined. It has been demonstrated to induce gremlin expression which in turn is known to inhibit the induction of differentiation by bone morphogenetic proteins. It is necessary in mouse-feeder cell dependent culture systems, as well as in feeder and serum-free culture systems. |
Source : | E.coli |
Species : | Human |
Form : | Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 16.5 kDa. The protein migrates as 17 kDa under reducing (R) condition (SDS-PAGE). |
Protein length : | 146 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >98% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | FGF2 |
Official Symbol : | FGF2 |
Synonyms : | FGF2; fibroblast growth factor 2 (basic); FGFB; fibroblast growth factor 2; prostatropin; heparin-binding growth factor 2; basic fibroblast growth factor bFGF; BFGF; FGF-2; HBGF-2 |
Gene ID : | 2247 |
mRNA Refseq : | NM_002006 |
Protein Refseq : | NP_001997 |
MIM : | 134920 |
UniProt ID : | P09038 |
Products Types
◆ Recombinant Protein | ||
FGF2-2185C | Recombinant Cattle FGF2 Protein, His-tagged | +Inquiry |
FGF2-022H | Active Recombinant Human FGF2 Protein | +Inquiry |
FGF2-77H | Recombinant Active Human FGF2 Protein, His-tagged(N-ter) | +Inquiry |
FGF2-3232M | Recombinant Mouse FGF2 Protein, His (Fc)-Avi-tagged | +Inquiry |
FGF2-401F | Active Recombinant Human FGF2 Protein (146 aa) | +Inquiry |
◆ Native Protein | ||
FGF2-34B | Active Native Bovine bFGF | +Inquiry |
FGF2-26551TH | Native Human FGF2 | +Inquiry |
◆ Lysates | ||
FGF2-638HCL | Recombinant Human FGF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionFGF2 promotes cell migration and angiogenesis and regulates bone homeostatic balance.
FGF2 is widely expressed in the nervous system.
FGF2 is mainly expressed in tissues such as mammary glands and ovaries of sheep.
FGF1 has a high degree of homology with FGF2.
FGF2 is involved in diseases such as cardiovascular disease, breast disease and bone homeostasis.
FGF2 negatively regulates bone homeostasis.
Customer Reviews (2)
Write a reviewThe technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.
The purchased protein is suitable for WB experiments and I am satisfied with the results.
Ask a Question for All FGF2 Products
Required fields are marked with *
My Review for All FGF2 Products
Required fields are marked with *
Inquiry Basket