"IL4" Related Products

Recombinant Human Interleukin-4, His Tag

Cat. No.: IL4-409H
Product Overview: Interleukin-4 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 150 amino acids fragment (25-153) and having a total molecular mass of 19.62kDa with an amino-terminal hexahistidine tag. The IL-4 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Description: Interleukin-4 is a pleiotropic cytokine produced primarily by activated T lymphocytes, basophils and mast cells. Multiple immune response-modulating functions are performed by IL-4 on a variety of cell types and it has an important role in the regulator of isotype switching, induction of IgE production in B lymphocytes and differentiation of precursor T helper cells. IL-4 binds to both membrane-bound and secreted soluble IL-4 receptors.
Source: Human
Host: Escherichia Coli.
Form: Interleukin-4 His-Tag is supplied in 1x PBS, 50% glycerol.
Purity: Greater than 95.0% as determined by SDS-PAGE.
Physical Appearance: Sterile Filtered clear solution.
Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS.
Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Gene Name: IL4 interleukin 4 [ Homo sapiens ]
Official Symbol: IL4
Synonyms: interleukin-4; binetrakin; pitrakinra; OTTHUMP00000066049; OTTHUMP00000066050; B cell growth factor 1; B_cell stimulatory factor 1; lymphocyte stimulatory factor 1
Gene ID: 3565
mRNA Refseq: NM_000589
Protein Refseq: NP_000580
UniProt ID: P05112
Chromosome Location: 5q31.1
Pathway: Allograft rejection; CD40/CD40L signaling; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signaling pathway
Function: cytokine activity; growth factor activity; interleukin-4 receptor binding; protein binding

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