Recombinant Human Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta), His-tagged
Cat.No. : | PSME2-1288H |
Product Overview : | Recombinant human PSME2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
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Cat. No. : | PSME2-1288H |
Description : | PSME2, also known as proteasome (prosome, macropain) activator subunit 2, is an IFN-gamma inducible proteasome activator required for presentation of certain major histocompatibility (MHC) class I antigens. Downregulation of PSME2 results in abnormal proteasome activation and has been implicated in the development of intimal hyperplasia (IH) in animal models. |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT, 0.1mM PMSF |
Molecular Weight : | 29.5 kDa (259aa), confirmed by MALDI-TOF |
Purity : | > 95% by SDS - PAGE |
Concentration : | 1.0 mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MAKPCGVRLS GEARKQVEVF RQNLFQEAEE FLYRFLPQKI IYLNQLLQED SLNVADLTSL RAPLDIPIPD PPPKDDEMET DKQEKKEVPK CGFLPGNEKV LSLLALVKPE VWTLKEKCIL VITWIQHLIP KIEDGNDFGV AIQEKVLERV NAVKTKVEAF QTTISKYFSE RGDAVAKASK ETHVMDYRAL VHERDEAAYG ELRAMVLDLR AFYAELYHII SSNLEKIVNP KGEEKPSMY |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | APC/C:Cdc20 mediated degradation of mitotic proteins; Antigen processing: Ubiquitination & Proteasome degradation; Apoptosis; Cell Cycle; DNA Replication Pre-Initiation |
Gene Name : | PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) [ Homo sapiens ] |
Official Symbol : | PSME2 |
Synonyms : | PSME2; proteasome (prosome, macropain) activator subunit 2 (PA28 beta); PA28B; REGbeta; PA28beta; proteasome activator complex subunit 2; REG-beta; OTTHUMP00000027977; MCP activator, 31-kD subunit; proteasome activator 28-beta; 11S regulator complex beta subunit; 11S regulator complex subunit beta; cell migration-inducing protein 22; proteasome activator 28 subunit beta; proteasome activator hPA28 subunit beta; activator of multicatalytic protease subunit 2; Proteasome activator complex subunit 2; 11S regulator complex subunit beta; Proteasome activator 28 subunit beta; Activator of multicatalytic protease subunit 2; PA28b |
Gene ID : | 5721 |
mRNA Refseq : | NM_002818 |
Protein Refseq : | NP_002809 |
MIM : | 602161 |
UniProt ID : | Q9UL46 |
Chromosome Location : | 14q11.2 |
Products Types
◆ Recombinant Protein | ||
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PSME2-4448R | Recombinant Rat PSME2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Psme2-5202M | Recombinant Mouse Psme2 Protein, Myc/DDK-tagged | +Inquiry |
PSME2-3676R | Recombinant Rhesus monkey PSME2 Protein, His-tagged | +Inquiry |
PSME2-5156H | Recombinant Human PSME2 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
PSME2-2741HCL | Recombinant Human PSME2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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