Recombinant Human Regulator Of Calcineurin 2, His-tagged
Cat.No. : | RCAN2-4750H |
Product Overview : | Recombinant human RCAN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | RCAN2-4750H |
Description : | Calcipressin-2, also known as RCAN2, belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFAT(nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. RCAN2 is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.2M NaCl |
Molecular Weight : | 24.1 kDa (217aa), confirmed by MALDI-TOF |
Purity : | > 85% by SDS - PAGE |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MPAPSMDCDV STLVACVVDV EVFTNQEVKE KFEGLFRTYD DCVTFQLFKS FRRVRINFSN PKSAARARIE LHETQFRGKK LKLYFAQVQT PETDGDKLHL APPQPAKQFL ISPPSSPPVG WQPINDATPV LNYDLLYAVA KLGPGEKYEL HAGTESTPSV VVHVCDSDIE EEEDPKTSPK PKIIQTRRPG LPPSVSN |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | Calcium signaling in the CD4+ TCR pathway; Role of Calcineurin-dependent NFAT signaling in lymphocytes |
Gene Name : | RCAN2 regulator of calcineurin 2 [ Homo sapiens ] |
Official Symbol : | RCAN2 |
Synonyms : | RCAN2; CSP2; RCN2; MCIP2; ZAKI4; hRCN2; ZAKI-4; DSCR1L1; regulator of calcineurin 2; calcipressin-2; OTTHUMP00000016544; Down syndrome candidate region 1-like 1; thyroid hormone-responsive protein ZAKI-4; Down syndrome critical region gene 1-like 1; thyroid hormone-responsive (skin fibroblasts); myocyte-enriched calcineurin-interacting protein 2; Calcipressin 2 (Thyroid hormone-responsive protein ZAKI-4) (Down syndrome candidate region 1-like 1) (Myocyte-enriched calcineurin interacting protein 2) (MCIP2) |
Gene ID : | 10231 |
mRNA Refseq : | NM_005822 |
Protein Refseq : | NP_005813 |
MIM : | 604876 |
UniProt ID : | Q14206 |
Chromosome Location : | 6p12.3 |
Function : | nucleotide binding; protein phosphatase 2B binding |
Products Types
◆ Recombinant Protein | ||
RCAN2-713H | Recombinant Human RCAN2 Protein, GST/His-tagged | +Inquiry |
RCAN2-4031H | Recombinant Human RCAN2 Protein, GST-tagged | +Inquiry |
RCAN2-4632R | Recombinant Rat RCAN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
RCAN2-4973R | Recombinant Rat RCAN2 Protein | +Inquiry |
RCAN2-12828Z | Recombinant Zebrafish RCAN2 | +Inquiry |
◆ Lysates | ||
RCAN2-2449HCL | Recombinant Human RCAN2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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