"SERPINA3" Related Products


Recombinant Human Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3

Cat. No.: SERPINA3-4587H
Product Overview: Human Alpha-1 AntiChymotrypsin produced from normal human serum having a molecular mass of 68kDa.
Description: Alpha 1 ACT is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. Alpha-1- ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer"s disease (AD) and in normal aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
Source: Human
Host: Human Serum.
Form: Lyophilized from 0.02M NH4HCO3.
Purity: Greater than 99.0%.
Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Solubility: It is recommended to reconstitute the lyophilized human A1ACT in phosphate buffer pH > 7.0 containing 0.15M NaCl.
Storage: Human SERPINA3 although stable at room temperature for 3 weeks, should be stored between 2-8°C.
Gene Name: SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 [ Homo sapiens ]
Official Symbol: SERPINA3
Synonyms: SERPINA3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; ACT; AACT; GIG24; GIG25; MGC88254; serpin peptidase inhibitor, clade A, member 3; alpha-1-antichymotrypsin; growth-inhibiting protein 24; growth-inhibiting protein 25; serine (or cysteine) proteinase inhibitor, clade A, member 3; Cell growth-inhibiting gene 24/25 protein; Alpha-1-antichymotrypsin His-Pro-less; antichymotrypsin
Gene ID: 12
mRNA Refseq: NM_001085
Protein Refseq: NP_001076
MIM: 107280
UniProt ID: P01011
Chromosome Location: 14q32.1
Pathway: Selenium Pathway
Function: DNA binding; peptidase inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity

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