Active Recombinant Mouse Sparc protein(Met1-Ile302), His-tagged
Cat.No. : | Sparc-4034M |
Product Overview : | Recombinant Mouse SPARC (NP_033268.1) (Met 1-Ile 302) was expressed in HEK293, with a polyhistidine tag at the C-terminus. |
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Source : | HEK293 |
Species : | Mouse |
Tag : | C-His |
Protein length : | Met1-Ile302 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its ability to inhibit the cell growth of Mv-1-Lu mink lung epithelial cells. The ED50 for this effect is typically 1-4 μg/mL. |
Molecular Mass : | The secreted recombinant mouse SPARC consists of 296 amino acids and has a predicted molecular mass of 34 kDa. In SDS-PAGE under reducing conditions, rm SPARC migrates as an approximately 43 kDa band due to glycosylation. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | > 96 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Sparc secreted acidic cysteine rich glycoprotein [ Mus musculus ] |
Official Symbol : | Sparc |
Synonyms : | SPARC; secreted acidic cysteine rich glycoprotein; ON; osteonectin; basement-membrane protein 40; secreted protein acidic and rich in cysteine; BM-40; AA517111; |
Gene ID : | 20692 |
mRNA Refseq : | NM_009242 |
Protein Refseq : | NP_033268 |
Products Types
◆ Recombinant Protein | ||
Sparc-8608M | Recombinant Mouse Sparc Protein, His (Fc)-Avi-tagged | +Inquiry |
SPARC-2725H | Recombinant Human SPARC Protein, His-tagged | +Inquiry |
Sparc-6073M | Recombinant Mouse Sparc Protein, Myc/DDK-tagged | +Inquiry |
SPARC-2503H | Recombinant Human SPARC Protein, MYC/DDK-tagged | +Inquiry |
SPARC-4111H | Recombinant Human SPARC Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
SPARC-30653TH | Native Human SPARC | +Inquiry |
SPARC-287B | Native Bovine Osteonectin | +Inquiry |
◆ Lysates | ||
SPARC-2616HCL | Recombinant Human SPARC cell lysate | +Inquiry |
SPARC-2120MCL | Recombinant Mouse SPARC cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionSPARC is associated with cancer progression, as it can influence tumor growth, invasion, and angiogenesis. Its expression levels in tumors are often studied for prognostic and diagnostic purposes.
Yes, SPARC is being explored as a therapeutic target for cancer. Researchers are investigating ways to modulate its activity to hinder tumor progression or enhance the efficacy of existing treatments.
SPARC expression can be detected through techniques like immunohistochemistry, Western blotting, and molecular assays. These methods help assess SPARC levels in tissues or blood samples.
SPARC plays a role in tissue repair by influencing cell-matrix interactions and modulating the extracellular environment. Its involvement in wound healing and tissue regeneration makes it a subject of interest in regenerative medicine.
Yes, there are clinical trials exploring the potential of targeting SPARC in various diseases, including cancer. These trials aim to evaluate the safety and efficacy of SPARC-modulating agents.
Customer Reviews (3)
Write a reviewThe SPARC protein finds great utility in protein electron microscopy structure analysis, consistently delivering exceptional results.
Its remarkable sensitivity and specificity make it a valuable tool for accurate and robust data analysis, bolstering the credibility of research outcomes.
Notably, it exhibits exceptional performance in ELISA assays, providing reliable and precise results in the detection and quantification of target molecules.
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