Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active Recombinant Human Teratocarcinoma-derived Growth Factor 1

Cat.No. : TDGF1-592H
Product Overview : TDGF1 Human Recombinant produced in HEK-293 cells is a single, glycosylated, polypeptide chain containing 139 amino acids with a molecular weight of 17.8 kDa though on SDS-PAGE migrates at about 25kDa due to the glycosilation. The TDGF1 is purified by proprietary chromatographic techniques.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : TDGF1-592H
Description : TDGF1 is an extracellular, membrane-bound signaling protein that is involved in embryonic development and tumor growth. Mutations in TDGF1 are associated with forebrain defects TDGF1 takes part in the determination of the epiblastic cells that later provide growth to the mesoderm.
Source : Human
Host : HEK293-F Cells.
Form : The TDGF1 protein was lyophilized from a 0.2µm filtered solution containing no additives or preservatives.
Purity : Greater than 95.0% as determined by SDS-PAGE.
Bio-activity : In a functional ELISA, immobilized recombinant human Activin RIB/Fc chimera receptor (0.2 µg/mL) will bind TDGF1 with linear range of 0.8 to 100 ng/ml.
Physical Appearance : Sterile Filtered White lyophilized (freeze-dried) powder.
Solubility : It is recommended to reconstitute the lyophilized TDGF1 in sterile 18Mμ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Amino acid sequence : LGHQEFARPS RGYLAFRDDS IWPQEEPAIR PRSSQRVPPM GIQHSKELNR TCCLNGGTCM LGSFCACPPS FYGRNCEHDV RKENCGSVPH DTWLPKKCSL CKCWHGQLRC FPQAFLPGCD GLVMDEHLVA SRTPELPPS.
Storage : Lyophilized TDGF1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution TDGF1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Gene Name : TDGF1 teratocarcinoma-derived growth factor 1 [ Homo sapiens ]
Official Symbol : TDGF1
Synonyms : TDGF1; teratocarcinoma-derived growth factor 1; CR; CRGF; CRIPTO; Cripto-1; Epidermal growth factor-like cripto protein CR1; Cripto-1 growth factor
Gene ID : 6997
mRNA Refseq : NM_003212
Protein Refseq : NP_003203
MIM : 187395
UniProt ID : P13385
Chromosome Location : 3p21.31
Function : growth factor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Is TDGF1 associated with any genetic disorders? 01/26/2021

Mutations in the TDGF1 gene have been linked to certain congenital disorders. Understanding these genetic associations can provide insights into the underlying mechanisms of these conditions.

How does TDGF1 influence neurodevelopment? 02/11/2020

TDGF1 has been found to play a role in neural development. It is involved in the specification of neural cell fate and the formation of the neural tube during embryogenesis.

Can TDGF1 be a target for drug development? 06/27/2019

Yes, efforts are underway to develop drugs that modulate TDGF1 activity. Targeting TDGF1 could potentially lead to novel therapies for conditions related to cell growth and differentiation.

In what ways does TDGF1 contribute to stem cell biology? 06/04/2019

TDGF1 is involved in the maintenance of pluripotency in embryonic stem cells. Understanding its role could enhance our ability to control and manipulate stem cells for therapeutic purposes.

How can TDGF1 be utilized in cancer diagnostics? 10/09/2016

Researchers are exploring the use of TDGF1 as a biomarker for certain cancers. Detection of elevated TDGF1 levels in patient samples may aid in early cancer diagnosis.

Customer Reviews (3)

Write a review
Reviews
01/13/2020

    the manufacturer can assist in sourcing complementary reagents and tools, such as specific antibodies or detection systems, to complement the use of TDGF1 protein in trials.

    03/26/2018

      manufacturers often have a wealth of knowledge and expertise in the field of TDGF1 protein research.

      08/29/2017

        They may offer educational resources such as technical guides, protocols, and application notes, which can aid researchers in understanding the principles, techniques, and potential applications of TDGF1 protein in their studies.

        Ask a Question for All TDGF1 Products

        Required fields are marked with *

        My Review for All TDGF1 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends