"IL1A" Related Products

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Recombinant Human IL1A

Cat. No.: IL1A-337H
Product Overview: Human IL1A (P01583, 113 a.a.-271 a.a.) partial recombinant protein expressed in Escherichia coli.
Description: Interleukin-1 alpha (IL-1μ) is a protein that in humans is encoded by the IL1A gene. The protein encoded by this gene is a cytokine of the interleukin-1 family. Interleukin-1 alpha possesses a wide spectrum of metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor.
Sequence: SAPFSFLS NVKYNFMRII KYEFILNDAL NQSIIRANDQ YLTAAALHNL DEAVKFDMGA YKSSKDDAKI TVILRISKTQ LYVTAQDEDQ PVLLKEMPEI PKTITGSETN LLFFWETHGT KNYFTSVAHP NLFIATKQDY WVCLAGGPPS ITDFQILENQ A
Theoretical MW (kDa): 18
Form: Lyophilized
Preparation Method: Escherichia coli expression system
Purity: > 97% by SDS-PAGE and HPLC
Endotoxin Level: < 0.1 ng/ug (1 EU/ug)
Activity: The ED50 was determined by the dose-dependent stimulation of murine D10S cells is μ 0.002 ng/mL, corresponding to a specific activity of μ 2 x 109 units/mg
Application: SDS-PAGE
Storage Buffer: Lyophilized from PBS, pH 7.0
Storage: Store at -20°C on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months. Aliquot to avoid repeated freezing and thawing.
Unitprot ID: P01583
Pathways: Apoptosis; Cytokine-cytokine receptor interaction; Graft-versus-host disease; Hematopoietic cell lineage; MAPK signaling pathway; Prion diseases; Type I diabetes mellitus
Gene Name: IL1A interleukin 1, alpha [ Homo sapiens ]
Official Symbol: IL1A
Synonyms: IL1A; interleukin 1, alpha; IL1; IL-1A; IL1F1; IL1-ALPHA; preinterleukin 1 alpha; hematopoietin-1; pro-interleukin-1-alpha; Interleukin-1 alpha; IL-1 alpha; Hematopoietin-1; IL1A (IL1F1)
Gene ID: 3552
mRNA Refseq: NM_000573
Protein Refseq: NP_000566
MIM: 147760
Chromosome Location: 2q14
Function: cytokine activity; interleukin-1 receptor binding; protein binding

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