"TGFA" Related Products

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Recombinant Human TGFA

Cat. No.: TGFA-538H
Product Overview: Human TGFA (P01135) full-elngth recombinant protein expressed in Hi-5 cells.
Description: Transforming growth factor alpha (TGF-μ) is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects . TGFμ stimulates neural cell proliferation in the adult injured brain.
Theoretical MW (kDa): 25
Form: Lyophilized
Preparation Method: Insect cell (Hi-5) expression system
Purity: μ 98% by SDS-PAGE, μ 98% by HPLC
Endotoxin Level: < 0.1 ng/ug
Activity: The ED50 as determined by the ability of TGF-beta2 to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells is < 0.2 ng/mL, corresponding to a specific activity of > 5 x 106 units/mg.
Application: SDS-PAGE
Storage Buffer: Lyophilized from sodium citrate, pH 3.5
Storage: Store at -20°C on dry atmosphere.
Unitprot ID: P01135
Gene Name: TGFA transforming growth factor, alpha [ Homo sapiens ]
Official Symbol: TGFA
Synonyms: TGFA; transforming growth factor, alpha; TFGA; protransforming growth factor alpha; transforming growth factor-alpha; TGF-alpha; EGF-like TGF; TGF type 1; ETGF
Gene ID: 7039
mRNA Refseq: NM_001099691
Protein Refseq: NP_001093161
MIM: 190170
Chromosome Location: 2p13
Pathway: ErbB signaling pathway; Glioma; Non-small cell lung cancer; Pancreatic cancer; Pathways in cancer; Prostate cancer; Renal cell carcinoma
Function: MAP kinase kinase activity; epidermal growth factor receptor binding; growth factor activity; protein binding; signal transducer activity

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