Cat. No. : | VEGFA-543H |
Product Overview : | Human VEGFA (NP_001020541, 207 a.a.-327 a.a.) partial recombinant protein with His tag expressed in Escherichia coli. |
Description : | Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. |
Sequence : | MGSSHHHHHH SSGLVPRGSH MAPMAEGGGQ NHHEVVKFMD VYQRSYCHPI ETLVDIFQEY PDEIEYIFKP SCVPLMRCGG CCNDEGLECV PTEESNITMQ IMRIKPHQGQ HIGEMSFLQH NKCECRPKKD RARQEKCDKP RR |
Theoretical MW (kDa) : | 16.3 |
Form : | Liquid |
Preparation Method : | E. coli expression system |
Purity : | > 95% by SDS-PAGE |
Endotoxin Level : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Activity : | The ED50 for this effect is < 4.2 ng/mL. Measured in a cell proliferation assay using NIH-3T3 cell. |
Application : | SDS-PAGE |
Storage Buffer : | In 20 mM Tris, pH 8.0 |
Storage : | Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C. |
Unitprot ID : | P15692 |
Gene Name : | VEGFA vascular endothelial growth factor A [ Homo sapiens ] |
Official Symbol : | VEGFA |
Synonyms : | VPF; VEGF; VEGFA_HUMAN; Vascular permeability factor; VEGF-A; VEGFA; MGC70609; Vegf120; Vegf164; Vegf188; vascular endothelial growth factor A; MGC70609; Vascular endothelial growth factor A precursor; Vascular permeability factor |
Gene ID : | 7422 |
mRNA Refseq : | NM_001025366 |
Protein Refseq : | NP_001020537 |
MIM : | 192240 |
Chromosome Location : | 6p12 |
Pathway : | Cytokine-cytokine receptor interaction; Focal adhesion; Pancreatic cancer; Renal cell carcinoma; VEGF signaling pathway; mTOR signaling pathway; Hemostasis; Signaling by VEGF. |
Function : | cell surface binding ;extracellular matrix binding; growth factor activity; growth factor activity; heparin binding; platelet-derived growth factor receptor binding; protein binding; protein homodimerization activity; vascular endothelial growth factor receptor binding. |
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