Recombinant Human DENR, His-tagged

• Cat.No.: DENR-3643H
• Product Overview: Recombinant human DENR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-198 aa).

Specification

• Cat. No.: DENR-3643H
• Description: DENR may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. This protein plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
• Form: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 20% glycerol, 2mM DTT, 0.15M NaCl.
• Molecular Weight: 24.3 kDa (218aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
• Purity: > 85 % by SDS - PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay )
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAADISESSG ADCKGDPRNS AKLDADYPLR VLYCGVCSLP TEYCEYMPDV AKCRQWLEKN FPNEFAKLTV ENSPKQEAGI SEGQGTAGEE EEKKKQKRGG RGQIKQKKKT VPQKVTIAKI PRAKKKYVTR VCGLATFEID LKEAQRFFAQ KFSCGASVTG EDEIIIQGDF TDDIIDVIQE KWPEVDDDSI EDLGEVKK
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: DENR density-regulated protein [ Homo sapiens ]
• Official Symbol: DENR
• Synonyms: DENR; DRP; DRP1; SMAP-3; density-regulated protein; OTTHUMP00000239609; OTTHUMP00000239610; smooth muscle cell associated protein-3; smooth muscle cell-associated protein 3
• Gene ID: 8562
• mRNA Refseq: NM_003677
• Protein Refseq: NP_003668
• MIM: 604550
• UniProt ID: O43583
• Chromosome Location: 12q24.31
• Function: molecular_function; protein binding; translation initiation factor activity