Recombinant Human Heat Shock Protein 90kDa Alpha (Cytosolic), Class B Member 1

• Cat.No.: HSP90AB1-4924H
• Product Overview: The recombinant HSP90AB1 produced from Sf9 cells represents the full length (a.a. 1-723) of Hsp90 subunit.

Specification

• Cat. No.: HSP90AB1-4924H
• Description: HSP90AB1 is a molecular chaperone and is one of the most abundant proteins in unstressed cells. In mammalian cells, there are two genes encoding cytosolic HSP90AB1 homologues, with the human Hsp90α showing 85% sequence identity to Hsp90β.
• Molecular Weight: 90 kDa
• Source: Sf9 cells
• Species: Human
• Form: 13 mg/ml in 40 mM HEPES/KOH, pH 7.5, containing 400 mM potassium chloride and 5% glycerol.
• Appearance: Liquid
• Endotoxin Level: < 0.1 ng/μg
• Purity: ≥99% by SDS-PAGE
• Storage: -80°C. Avoid freeze/thaw cycles.
• Pathways: Antigen processing and presentation; NOD-like receptor signaling pathway; Pathways in cancer; Progesterone-mediated oocyte maturation; Prostate cancer; Axon guidance; Immune System; Inflammasomes; Innate Immunity Signaling; Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways; Progesterone-mediated oocyte maturation; Protein processing in endoplasmic reticulum; Sema3A PAK dependent Axon repulsion; Semaphorin interactions; TNF-alpha/NF-kB Signaling Pathway

Gene Information

• Gene Name: HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 [ Homo sapiens ]
• Official Symbol: HSP90AB1
• Synonyms: HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1; HSPC2; HSPCB; D6S182; HSP90B; FLJ26984; HSP90-BETA; heat shock protein HSP 90-beta; heat shock protein HSP 90-beta; HSP84; HSP 84; HSP 90; Heat shock 84 kDa; OTTHUMP00000016517; OTTHUMP00000016518; OTTHUMP00000016519; heat shock protein beta; heat shock 90kD protein 1, beta; 90-kda heat shock protein beta HSP90 beta
• Gene ID: 3326
• mRNA Refseq: NM_007355
• Protein Refseq: NP_031381
• MIM: 140572
• UniProt ID: P08238
• Chromosome Location: 6p12
• Function: ATP binding; TPR domain binding; nitric-oxide synthase regulator activity; nucleotide binding; unfolded protein binding; CTP binding; GTP binding; UTP binding; dATP binding; protein binding; protein serine/threonine kinase activity