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Recombinant Rat Insulin-Like Growth Factor 1

Cat.No. : Igf1-604R
Product Overview : Rat Igf1 is a 7.69 kDa protein containing 70 amino acid residues (plus an additional 21 aa as N terminal His tag).
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Cat. No. : Igf1-604R
Description : Igf1 (Insulin like Growth Factor 1) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue.
Biological Activity : The ED₅₀ was determined by two methods: 1) By stimulation of protein synthesis in rat L6 myoblasts, the ED₅₀ was found to be <30 ng/ml; 2) By Type I IGF receptor binding assay, the ED₅₀ was found to be <10 ng/ml.
Molecular Weight : 7.69 kDa
Source : E. coli
Species : Rat
Form : Lyophilized without additives.
Appearance : Liquid
Endotoxin Level : <0.1 ng/μg
Reconstitution : Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
Purity : ≥95% by SDS-PAGE and HPLC analyses
Storage : The lyophilized Igf1 is best stored desiccated below 0°C. Reconstituted Igf1 should be stored at working aliquots at 20°C.
Pathways : Adipogenesis; Aldosterone-regulated sodium reabsorption; Androgen receptor signaling pathway; Apoptosis; Diabetes pathways; Dilated cardiomyopathy; Hypertrophic cardiomyopathy (HCM); Long-term depression; Melanoma; Pathways in cancer; Prostate cancer; mTOR signaling pathway; p53 signaling pathway; Focal adhesion; Glioma
Gene Name : Igf1 insulin-like growth factor 1 [ Rattus norvegicus ]
Official Symbol : Igf1
Synonyms : Igf1; insulin-like growth factor 1; IGF1; IGF-I; IGFI; IBP1; IGF-IA; IGFIA; IGF-IB; MGF; Somatomedin C; Somatomedin-C; Mechano growth factor; insulin-like growth factor 1 (somatomedin C); somatomedin; insulin-like growth factor I
Gene ID : 24482
mRNA Refseq : NM_001082477
Protein Refseq : NP_001075946
UniProt ID : P08025
Chromosome Location : 7q12-q13
Function : growth factor activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; protein binding; steroid binding; integrin binding; protein serine/threonine kinase activator activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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04/23/2022

    Range of applications of IGF1 is breathtaking, and it can play its unique advantage in any field.

    08/18/2021

      The biological activity and high purity of the protein are impressive, which is why it is a trusted partner in the field of scientific research.

      06/13/2021

        IGF1 can preserve its stability under extreme conditions, such as at high or low temperatures, which is very beneficial for our experiments.

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