"Pgf" Related Products


Recombinant Mouse Placental Growth Factor

Cat. No. : Pgf-606M
Product Overview : Recombinant human Pgf is a 32.6 kDa homodimeric protein consisting of two 142 amino acid polypeptide chains.
Description : Pgf is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. Pgf is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration.
Biological Activity : Determined by its ability to chemoattract human monocytes of using a concentration range of 0.5-10 ng/ml.
Molecular Weight : 32.6 kDa
Source : E. coli
Species : Mouse
Form : Sterile filtered and lyophilized without additives.
Endotoxin Level : <0.1 ng/μg
Appearance : Lyophilized protein
Reconstitution : Reconstitute the protein in sterile 20 mM acetic acid to a concentration of 0.1-1.0 μg/μl. The solution can then be diluted into other aqueous buffer.
Purity : >98% by SDS-PAGE and ≥95% by HPLC
Storage : The lyophilized protein is best-stored desiccated below 0°C. Reconstituted protein should be stored at working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA). Prevent freeze/thaw cycles.
Gene Name : Pgf placental growth factor [ Mus musculus ]
Official Symbol : Pgf
Synonyms : Pgf; placental growth factor; PIGF; Plgf; AI854365; placenta growth factor
Gene ID : 18654
mRNA Refseq : NM_008827
Protein Refseq : NP_032853
UniProt ID : P49764
Chromosome Location : 12 D
Pathway : Bladder cancer; Focal Adhesion; Focal adhesion; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; Rheumatoid arthritis; Signaling by VEGF; VEGF binds to VEGFR leading to receptor dimerization; VEGF ligand-receptor interactions; mTOR signaling pathway
Function : growth factor activity; protein heterodimerization activity

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