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Recombinant Human Vascular Endothelial Growth Factor C, His-tagged

Cat. No.: VEGFC-615H
Product Overview: The recombinant human protein contains N-terminal and C-terminal His-tags (167 aa, MW 18.772 kDa).
Description: The recombinant VEGFC (Vascular Endothelial Growth Factor-C) lacks the N-terminal signal peptide and includes amino acids from T103 to R227 of Gene Bank U58111.
Biological Activity: Activity of VEGFC is tested by the stimulation of VEGF-R3 phosphorylation in cells transfected with VEGF-R3. The expected ED50 is > 200 ng/ml.
Molecular Weight: 18.772 kDa
Source: E. coli
Species: Human
Form: Lyophilized without additives.
Appearance: Lyophilized protein
Endotoxin Level: <0.1 ng/μg
Reconstitution: We recommend a quick spin followed by reconstitution in 0.1% acetic acid to a concentration of 0.1-1.0 mg/ml. The solution should be stored at -70°C.
Purity: >90% by SDS-PAGE analyses.
Storage: The lyophilized VEGFC is best-stored at -20°C. Reconstituted VEGFC should be stored in working aliquots at -70°C.
Pathways: Bladder cancer; Cytokine-cytokine receptor interaction; Focal Adhesion; Focal adhesion; Formation of Platelet plug; Heart Development; Hemostasis; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; Response to elevated platelet cytosolic Ca2+; Signaling by VEGF; Signaling events mediated by VEGFR1 and VEGFR2; VEGF ligand-receptor interactions; VEGFR3 signaling in lymphatic endothelium; mTOR signaling pathway
Gene Name: VEGFC vascular endothelial growth factor C [ Homo sapiens ]
Official Symbol: VEGFC
Synonyms: VEGFC; vascular endothelial growth factor C; RP; Flt4-L; VEGF-C; FLT4 ligand DHM; OTTHUMP00000218843; vascular endothelial growth factor-related protein; VRP; Flt4 ligand
Gene ID: 7424
mRNA Refseq: NM_005429
Protein Refseq: NP_005420
MIM: 601528
UniProt ID: P4976
Chromosome Location: 4q34.3
Function: chemoattractant activity; growth factor activity; protein binding; vascular endothelial growth factor receptor 3 binding

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