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Recombinant Human Interleukin 5 (Colony-Stimulating Factor, Eosinophil)

Cat.No. : IL5-528H
Product Overview : Recombinant human IL-5 is a 26.5 kDa protein containing 232 amino acid residues.
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  • Gene Information
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Cat. No. : IL5-528H
Description : IL-5 is a potent T-cell derived factor that stimulates the growth of certain B cells and the differentiation of eosinophils.
Biological Activity : The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is <0.15 ng/ml, corresponding to a specific activity of >6x106 units/mg.
Molecular Weight : 26.5 kDa
Source : E. coli
Species : Human
Form : Lyophilized (from 1 mg/ml in 0.4X PBS)
Appearance : Lyophilized protein
Endotoxin Level : <0.1 ng/μg
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1 mg/ml. The solution can be diluted into other buffered solutions or stored at -20°C for future use. For most in vitro applications, IL-5 exerts its biological activity in the concentration range of 0.1 to 10 ng/ml.
Purity : >98% by SDS-PAGE and HPLC analysis
Storage : The lyophilized IL-5 is best-stored desiccated below 0°C. Reconstituted IL-5 should be stored at working aliquots at -20°C. For long-term storage, it is recommended to add a carrier protein (0.1% HAS or BSA). Avoid freeze/thaw cycles.
Pathways : Allograft rejection; Asthma; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signaling pathway; cell receptor signaling pathway
Gene Name : IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ]
Official Symbol : IL5
Synonyms : IL5; interleukin 5 (colony-stimulating factor, eosinophil); EDF; TRF; IL-5; interleukin-5; OTTHUMP00000065830; T-cell replacing factor; B cell differentiation factor I; B-cell differentiation factor I; eosinophil differentiation factor; Eosinophil differentiation factor
Gene ID : 3567
mRNA Refseq : NM_000879
Protein Refseq : NP_000870
MIM : 147850
UniProt ID : P05113
Chromosome Location : 5q31.1
Function : cytokine activity; growth factor activity; interleukin-4 receptor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Which effect of IL5 in the treatment of tuberous sclerosis? 08/07/2022

Inhibit the creatinine kinase level in the blood of patients with tuberous sclerosis, reduce the inflammatory response, and improve the quality of life of patients.

Does there have any effect of IL5 in the treatment of allergic rhinitis? 07/07/2022

IL5 can reduce the number of eosinophils in the nasal mucosa of patients with allergic rhinitis, reducing the symptoms of allergic reactions, such as sneezing, runny nose and nasal congestion.

What is the main function of IL5? 03/04/2022

Stimulate the proliferation and differentiation of white blood cells, promote the function of the immune system, and is used to treat diseases such as asthma, allergic rhinitis, nodular sclerosis and some malignant tumors.

Does IL5 have side effects? 10/26/2019

Cause mild side effects such as headache, nausea, vomiting, and serious side effects such as allergic reactions if the dose is too large or allergic.

Can IL5 be administered orally? 07/24/2019

IL5 cannot be administered orally, only by injection or intravenous drip.

What is the effect of IL5 in the treatment of asthma? 02/14/2019

IL5 can reduce the number of eosinophils in the lungs of asthma patients, reduce the frequency and severity of asthma attacks, and improve the quality of life of patients.

Customer Reviews (3)

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Reviews
07/26/2022

    High efficacy and safety in clinical treatment.

    06/22/2022

      There are no structural or functional defects.

      01/31/2019

        The stability and activity are maintained well during long-term storage.

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