Recombinant Human Interleukin 5 (Colony-Stimulating Factor, Eosinophil)
Cat.No. : | IL5-528H |
Product Overview : | Recombinant human IL-5 is a 26.5 kDa protein containing 232 amino acid residues. |
- Specification
- Gene Information
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Cat. No. : | IL5-528H |
Description : | IL-5 is a potent T-cell derived factor that stimulates the growth of certain B cells and the differentiation of eosinophils. |
Biological Activity : | The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is <0.15 ng/ml, corresponding to a specific activity of >6x106 units/mg. |
Molecular Weight : | 26.5 kDa |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized (from 1 mg/ml in 0.4X PBS) |
Appearance : | Lyophilized protein |
Endotoxin Level : | <0.1 ng/μg |
Reconstitution : | Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1 mg/ml. The solution can be diluted into other buffered solutions or stored at -20°C for future use. For most in vitro applications, IL-5 exerts its biological activity in the concentration range of 0.1 to 10 ng/ml. |
Purity : | >98% by SDS-PAGE and HPLC analysis |
Storage : | The lyophilized IL-5 is best-stored desiccated below 0°C. Reconstituted IL-5 should be stored at working aliquots at -20°C. For long-term storage, it is recommended to add a carrier protein (0.1% HAS or BSA). Avoid freeze/thaw cycles. |
Pathways : | Allograft rejection; Asthma; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signaling pathway; cell receptor signaling pathway |
Gene Name : | IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ] |
Official Symbol : | IL5 |
Synonyms : | IL5; interleukin 5 (colony-stimulating factor, eosinophil); EDF; TRF; IL-5; interleukin-5; OTTHUMP00000065830; T-cell replacing factor; B cell differentiation factor I; B-cell differentiation factor I; eosinophil differentiation factor; Eosinophil differentiation factor |
Gene ID : | 3567 |
mRNA Refseq : | NM_000879 |
Protein Refseq : | NP_000870 |
MIM : | 147850 |
UniProt ID : | P05113 |
Chromosome Location : | 5q31.1 |
Function : | cytokine activity; growth factor activity; interleukin-4 receptor binding |
Products Types
◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionInhibit the creatinine kinase level in the blood of patients with tuberous sclerosis, reduce the inflammatory response, and improve the quality of life of patients.
IL5 can reduce the number of eosinophils in the nasal mucosa of patients with allergic rhinitis, reducing the symptoms of allergic reactions, such as sneezing, runny nose and nasal congestion.
Stimulate the proliferation and differentiation of white blood cells, promote the function of the immune system, and is used to treat diseases such as asthma, allergic rhinitis, nodular sclerosis and some malignant tumors.
Cause mild side effects such as headache, nausea, vomiting, and serious side effects such as allergic reactions if the dose is too large or allergic.
IL5 cannot be administered orally, only by injection or intravenous drip.
IL5 can reduce the number of eosinophils in the lungs of asthma patients, reduce the frequency and severity of asthma attacks, and improve the quality of life of patients.
Customer Reviews (3)
Write a reviewHigh efficacy and safety in clinical treatment.
There are no structural or functional defects.
The stability and activity are maintained well during long-term storage.
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