Recombinant Human Interleukin 5 (Colony-Stimulating Factor, Eosinophil) IL5-528H

Recombinant Human Interleukin 5 (Colony-Stimulating Factor, Eosinophil)

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Recombinant Human Interleukin 5 (Colony-Stimulating Factor, Eosinophil)

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Cat. No. : IL5-528H
Product Overview : Recombinant human IL-5 is a 26.5 kDa protein containing 232 amino acid residues.
Description : IL-5 is a potent T-cell derived factor that stimulates the growth of certain B cells and the differentiation of eosinophils.
Biological Activity : The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is <0.15 ng/ml, corresponding to a specific activity of >6x106 units/mg.
Molecular Weight : 26.5 kDa
Source : E. coli
Species : Human
Form : Lyophilized (from 1 mg/ml in 0.4X PBS)
Appearance : Lyophilized protein
Endotoxin Level : <0.1 ng/μg
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1 mg/ml. The solution can be diluted into other buffered solutions or stored at -20°C for future use. For most in vitro applications, IL-5 exerts its biological activity in the concentration range of 0.1 to 10 ng/ml.
Purity : >98% by SDS-PAGE and HPLC analysis
Storage : The lyophilized IL-5 is best-stored desiccated below 0°C. Reconstituted IL-5 should be stored at working aliquots at -20°C. For long-term storage, it is recommended to add a carrier protein (0.1% HAS or BSA). Avoid freeze/thaw cycles.
Pathways : Allograft rejection; Asthma; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signaling pathway; cell receptor signaling pathway
Gene Name : IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ]
Official Symbol : IL5
Synonyms : IL5; interleukin 5 (colony-stimulating factor, eosinophil); EDF; TRF; IL-5; interleukin-5; OTTHUMP00000065830; T-cell replacing factor; B cell differentiation factor I; B-cell differentiation factor I; eosinophil differentiation factor; Eosinophil differentiation factor
Gene ID : 3567
mRNA Refseq : NM_000879
Protein Refseq : NP_000870
MIM : 147850
UniProt ID : P05113
Chromosome Location : 5q31.1
Function : cytokine activity; growth factor activity; interleukin-4 receptor binding

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