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Recombinant Human OTOR protein

Cat.No. : OTOR-4933H
Product Overview : Recombinant Human OTOR protein was expressed in Escherichia coli.
  • Specification
  • Gene Information
  • Related Products
Description : OTOR also named Otoraplin and MIAL, is a 15 kDa disulfide bonded homodimer, which is secreted via the Golgi apparatus and is a member of the MIA/OTOR family. Members of this family which also includes MIA, MIA2, and TANGO share a Src homology-3 (SH3)-like domain. OTOR is mainly expressed in the cochlea of the inner-ear and appears to be involved in early chondrogenesis of the otic capsule, which is required for normal inner ear development and auditory function. The OTOR shares high sequence identity with the mouse (90%), chicken (80%), and bullfrog (60%) orthologs and with the related human CDRAP/MIA protein (43%).
Source : E.coli
Species : Human
Form : Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB, pH 7.4, 150mM NaCl.
Molecular Mass : Approximately 12.7 kDa, a single non-glycosylated polypeptide chain containing 111 amino acids.
Protein length : 111
AA Sequence : VHGIFMDRLASKKLCADDECVYTIS LASAQEDYNAPDCRFINVKKGQQIY VYSKLVKENGAGEFWAGSVYGDGQD EMGVVGYFPRNLVKEQRVYQEATKE VPTTDIDFFCE
Endotoxin : Less than 1 EU/µg of rHuOTOR as determined by LAL method.
Purity : >97% by SDS-PAGE and HPLC analysis.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : OTOR
Official Symbol : OTOR
Synonyms : OTOR; otoraplin; FDP; MIAL; MIAL1; fibrocyte-derived protein; melanoma inhibitory activity-like protein; MGC126737; MGC126739;
Gene ID : 56914
mRNA Refseq : NM_020157
Protein Refseq : NP_064542
MIM : 606067
UniProt ID : Q9NRC9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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