"HSF1" Related Products

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Recombinant Human Heat Shock Transcription Factor 1, GST-tagged

Cat. No.: HSF1-4849H
Product Overview: Recombinant full length human HSF1 was expressed in E. coli cells using a N-terminal GST tag.
Description: HSF1 is a member of the heat shock transcription factor family. Protein-damaging stress lead to the activation of HSF1 which binds to upstream regulatory sequences in the promoters of heat shock genes leading to enhanced heat shock gene expression. The activation of HSF1 proceeds through a multi-step pathway, involving a monomer-to-trimer transition, nuclear accumulation and extensive posttranslational modifications.
Applications: Kinase Assay; Western Blot
Molecular Weight: 96 kDa
Expression System: E. coli
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity: >90%
Concentration: 0.2 ug/ul
Sequences: Full length
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: HSF1 heat shock transcription factor 1 [ Homo sapiens ]
Official Symbol: HSF1
Synonyms: HSF1; heat shock transcription factor 1; HSTF1; heat shock factor protein 1; HSF 1; HSTF 1; OTTHUMP00000228553; OTTHUMP00000228555
Gene ID: 3297
mRNA Refseq: NM_005526
Protein Refseq: NP_005517
MIM: 140580
UniProt ID: Q00613
Chromosome Location: 8q24
Function: protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity

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