"KAT5" Related Products

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Recombinant Human K(lysine) Acetyltransferase 5, GST-tagged

Cat. No.: KAT5-1599H
Product Overview: Recombinant full-length human KAT5 (TIP60) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: KAT5 or K (lysine) acetyltransferase 5 is a signaling protein that belongs to the MYST family of histone acetyl transferases (HATs). KAT5 was originally isolated as an HIV-1 TAT-interactive protein that plays an important role in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. KAT5 protein is a histone acetylase that is involved in DNA repair and apoptosis and plays an important role in signal transduction. KAT5 acts as a cofactor of TAT that is involved in the regulation of HIV gene expression. KAT5 is also a co-regulator of transcription factors that either promote or suppress tumorigenesis.
Applications: Western Blot
Molecular Weight: 88 kDa
Expression System: Sf9 insect cells using baculovirus
Species: Human
Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0,25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity: > 90 %
Concentration: 0.1 ug/ul
Sequences: Full length
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: ATF-2 transcription factor network; Androgen Receptor Signaling Pathway; C-MYC pathway; HTLV-I infection; IL-9 Signaling Pathway; Regulation of Androgen receptor activity; Validated targets of C-MYC transcriptional activation; p53 pathway
Gene Name: KAT5 K(lysine) acetyltransferase 5 [ Homo sapiens ]
Official Symbol: KAT5
Synonyms: KAT5; K(lysine) acetyltransferase 5; TIP; ESA1; PLIP; TIP60; cPLA2; HTATIP; HTATIP1; histone acetyltransferase KAT5; OTTHUMP00000233811; OTTHUMP00000233812; OTTHUMP00000233813; OTTHUMP00000233848; K-acetyltransferase 5; cPLA2 interacting protein; lysine acetyltransferase 5; cPLA(2)-interacting protein; 60 kDa Tat-interactive protein; Tat interacting protein, 60kDa; histone acetyltransferase HTATIP; HIV-1 Tat interactive protein, 60kDa; NP_001193762.1; NP_006379.2; NP_874368.1; NP_874369.1; EC 2.3.1.48; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein, 60kDa
Gene ID: 10524
mRNA Refseq: NM_006388
Protein Refseq: NP_006379
MIM: 601409
UniProt ID: Q92993
Chromosome Location: 11q13
Function: androgen receptor binding; contributes_to histone acetyltransferase activity; metal ion binding; protein binding; repressing transcription factor binding; transcription coactivator activity; transferase activity, transferring acyl groups other than amino-acyl groups

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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