Recombinant Human PADI4 protein, GST-tagged
Cat.No. : | PADI4-1608 |
Product Overview : | Recombinant Human PADI4 fussed with GST tag at N-terminal was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~96 kDa |
Protein length : | Full Length |
Purity : | >95 % |
Applications : | Western Blot |
Stability : | 1 yr at -70 centigrade from date of shipment |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 ug/ul |
Shipping : | Product shipped on dry ice |
Gene Name : | PADI4 peptidyl arginine deiminase, type IV [ Homo sapiens ] |
Official Symbol : | PADI4 |
Synonyms : | PADI4; peptidyl arginine deiminase, type IV; PADI5, peptidyl arginine deiminase, type V; protein-arginine deiminase type-4; PAD; PDI4; PDI5; HL-60 PAD; PADI-H protein; protein-arginine deiminase type IV; peptidyl arginine deiminase, type V; PAD4; PADI5; |
Gene ID : | 23569 |
mRNA Refseq : | NM_012387 |
Protein Refseq : | NP_036519 |
MIM : | 605347 |
UniProt ID : | Q9UM07 |
Chromosome Location : | 1p36.13 |
Pathway : | protein citrullination, organism-specific biosystem; protein citrullination, conserved biosystem; |
Function : | calcium ion binding; hydrolase activity; protein-arginine deiminase activity; |
Products Types
◆ Recombinant Protein | ||
PADI4-001H | Recombinant Human PADI4 Protein, His/GST-tagged | +Inquiry |
Padi4-11M | Recombinant Mouse Padi4 Protein, His-tagged | +Inquiry |
PADI4-313H | Recombinant Human PADI4 Protein, His-tagged | +Inquiry |
PADI4-1599H | Recombinant Human PADI4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Padi4-038M | Recombinant Mouse Padi4 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PADI4-630HCL | Recombinant Human PADI4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionPADI4 is predominantly expressed in various tissues, including synovial tissues, immune cells, and certain epithelial cells.
PADI4 plays a crucial role in citrullination, a process that converts arginine residues to citrulline, influencing protein structure and function.
Peptidyl arginine deiminase 4 (PADI4) primarily functions in cellular processes, contributing to the post-translational modification of proteins through citrullination.
In the regulation of immune responses, PADI4 is implicated in autoimmune diseases such as rheumatoid arthritis, where it contributes to autoantibody generation.
Dysregulation or abnormal expression of PADI4 is associated with autoimmune disorders, particularly rheumatoid arthritis.
There are potential therapeutic implications related to targeting PADI4 in autoimmune disorders, making it a focus for drug development.
Specific substrates of PADI4 include histones and other proteins, impacting cellular processes like gene regulation and signaling pathways.
Customer Reviews (3)
Write a reviewThe minimal variation across different batches enhanced the repeatability of our results.
The product's role in promoting collaboration and teamwork positively impacted the quality of our research.
The product's compatibility with various instruments and techniques promoted teamwork in our interdisciplinary projects.
Ask a Question for All PADI4 Products
Required fields are marked with *
My Review for All PADI4 Products
Required fields are marked with *
Inquiry Basket