"PTPRA" Related Products

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Recombinant Human Protein Tyrosine Phosphatase, Receptor Type, A, GST-tagged

Cat. No.: PTPRA-1621H
Product Overview: Recombinant human PTPRA (174-802) was expressed in E. coli cells using an N-terminal GST tag.
Description: PTPRA is a member of the protein tyrosine phosphatase family and contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. PTPRA dephosphorylates SRC family kinases, potassium channels and NMDA receptors and exists as three alternatively spliced variants which encode two distinct isoforms.
Applications: Phosphatase Assay; Western Blot
Molecular Weight: 96 kDa
Expression System: E. coli
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
Specific Activity: 2117 nmol/min/mg
Purity: > 90 %
Concentration: 0.1 ug/ul
Sequences: 174-802
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: Axon guidance; Insulin Pathway; NCAM signaling for neurite out-growth
Gene Name: PTPRA protein tyrosine phosphatase, receptor type, A [ Homo sapiens ]
Official Symbol: PTPRA
Synonyms: PTPRA; protein tyrosine phosphatase, receptor type, A; LRP; HLPR; PTPA; HEPTP; HPTPA; RPTPA; PTPRL2; HPTPalpha; R-PTP-alpha; receptor-type tyrosine-protein phosphatase alpha; PTPase-alpha; OTTHUMP00000030063; OTTHUMP00000030064; OTTHUMP00000030065; PTPLCA-related phosphatase; tyrosine phosphatase alpha; protein-tyrosine phosphatase alpha; protein tyrosine phosphatase, receptor type, alpha polypeptide; Leukocyte common antigen-related peptide (protein tyrosine phosphate); EC 3.1.3.48; Receptor-type tyrosine-protein phosphatase alpha; Protein-tyrosine phosphatase alpha
Gene ID: 5786
mRNA Refseq: NM_002836
Protein Refseq: NP_002827
MIM: 176884
UniProt ID: P18433
Chromosome Location: 20p13
Function: hydrolase activity; protein tyrosine phosphatase activity; receptor activity; transmembrane receptor protein tyrosine phosphatase activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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