Recombinant Human Signal Transducer And Activator Of Transcription 4, His-tagged
Cat.No. : | STAT4-4888H |
Product Overview : | Recombinant full-length human STAT4 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | STAT4-4888H |
Description : | STAT4 (signal transducer and activator of transcription 4) is a member of the STAT family that is phosphorylated by receptor-associated protein kinases. STATs form homo- or heterodimers and translocate to the cell nucleus where they act as transcription activators. T helper (Th) cells differentiation is regulated by STAT4. STAT4 controls T1/T2 balance during the response to live influenza virus and isolated viral proteins. The differentiation of gamma interferon (IFN-γ)-producing Th1 and Tc1 cells after inoculation of live virus occurred independently of STAT4 expression. STAT4 has been shown to control pathogenesis of chronic obstructive pulmonary disease. |
Applications : | Kinase Assay; Western Blot |
Molecular Weight : | 87 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol. |
Purity : | > 95 % |
Concentration : | 0.2 ug/ul |
Sequences : | Full-length |
Storage : | Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | Jak-STAT signaling pathway |
Gene Name : | STAT4 signal transducer and activator of transcription 4 [ Homo sapiens ] |
Official Symbol : | STAT4 |
Synonyms : | STAT4; signal transducer and activator of transcription 4; SLEB11; OTTHUMP00000163553 |
Gene ID : | 6775 |
mRNA Refseq : | NM_003151 |
Protein Refseq : | NP_003142 |
MIM : | 600558 |
UniProt ID : | Q14765 |
Chromosome Location : | 2q32.2-q32.3 |
Function : | calcium ion binding; protein binding; signal transducer activity; transcription factor activity |
Products Types
◆ Recombinant Protein | ||
STAT4-2898H | Recombinant Human STAT4 Protein, MYC/DDK-tagged | +Inquiry |
Stat4-6171M | Recombinant Mouse Stat4 Protein, Myc/DDK-tagged | +Inquiry |
STAT4-8787M | Recombinant Mouse STAT4 Protein, His (Fc)-Avi-tagged | +Inquiry |
STAT4-2116H | Recombinant Human STAT4 Protein, His (Fc)-Avi-tagged | +Inquiry |
STAT4-30118TH | Recombinant Human STAT4 | +Inquiry |
◆ Lysates | ||
STAT4-488HCL | Recombinant Human STAT4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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