Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Zeta Polypeptide

Cat.No. : YWHAZ-4901H
Product Overview : Recombinant full-length human tag-free YWHAZ was expressed in E. coli cells.
  • Specification
  • Gene Information
  • Related Products
Cat. No. : YWHAZ-4901H
Description : YWHAZ (also known as tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide) is a member of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. YWHAZ protein plays a key role in cancer biology by being an important regulator of major cellular processes such as proliferation, differentiation, senescence and apoptosis. YWHAZ protein has been shown to interact with the IRS1 protein, suggesting a role for this protein in regulating insulin sensitivity by interrupting the association between the insulin receptor and IRS1.
Applications : Western Blot
Molecular Weight : 29kDa
Expression System : E.coli
Species : Human
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity : >95 %
Concentration : 0.2ug/ul
Sequences : Full-length
Storage : Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways : Adaptive Immunity Signaling; Alpha6-Beta4 Integrin Signaling Pathway; Calcium Regulation in the Cardiac Cell; Cell cycle; Class I PI3K signaling events mediated by Akt; Cytokine Signaling in Immune system; Destabilization of mRNA by KSRP; ErbB1 downstream signaling; Formation of Platelet plug; FoxO family signaling; GP1b-IX-V activation signalling; Hemostasis; IGF1 pathway; IL-3 Signaling Pathway; IL-5 Signaling Pathway
Gene Name : YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide [ Homo sapiens ]
Official Symbol : YWHAZ
Synonyms : YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; KCIP-1; MGC111427; MGC126532; MGC138156; phospholipase A2; 14-3-3 zeta; 14-3-3 protein/cytosolic phospholipase A2; Protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide; OTTHUMP00000165851; OTTHUMP00000165852; OTTHUMP00000165854; OTTHUMP00000165858; OTTHUMP00000165859; OTTHUMP00000165860; YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
Gene ID : 7534
mRNA Refseq : NM_001135699
Protein Refseq : NP_001129171
MIM : 601288
UniProt ID : P63104
Chromosome Location : 8q23.1
Function : protein binding; protein domain specific binding; transcription factor binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
How does YWHAZ contribute to cardiovascular diseases? 09/03/2021

YWHAZ is involved in cardiovascular diseases by influencing processes like vascular smooth muscle cell proliferation and apoptosis.

Are there diagnostic applications of YWHAZ in cancer detection? 04/11/2021

Yes, elevated levels of YWHAZ protein have been detected in certain cancers, making it a potential biomarker for cancer diagnosis.

Is YWHAZ a potential biomarker for cardiovascular diseases? 01/27/2018

Preliminary studies suggest that YWHAZ levels may be altered in cardiovascular diseases, making it a candidate biomarker for further investigation.

Can YWHAZ protein be targeted for cancer treatment? 03/27/2016

Research suggests that targeting YWHAZ protein may be a viable strategy for developing anticancer therapies.

Are there potential therapeutic interventions targeting YWHAZ in neurodegenerative disorders? 03/18/2016

Investigational studies are exploring the modulation of YWHAZ as a potential therapeutic approach for neurodegenerative disorders.

Customer Reviews (3)

Write a review
Reviews
10/17/2022

    I greatly appreciate their commitment to ensuring my research is a success.

    01/01/2022

      The YWHAZ Protein offers a wide range of applications, making it highly versatile for various experimental settings.

      11/16/2020

        With the YWHAZ Protein, I have the confidence to generate critical insights and drive significant advancements in my field.

        Ask a Question for All YWHAZ Products

        Required fields are marked with *

        My Review for All YWHAZ Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends