Recombinant Human 2,4-Dienoyl CoA Reductase 2, Peroxisomal, His-tagged DECR2-1330H

Cat. No.:	DECR2-1330H
Product Overview:	Recombinant human DECR2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description:	DECR2, also known as peroxisomal 2,4-dienoyl-CoA reductase, is an auxiliary enzyme of beta-oxidation. DECR2 participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. This protein catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
Form:	Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 40% glycerol, 0.15 M NaCl.
Molecular Weight:	33.2 kDa (315 aa) confirmed by MALDI-TOF
Purity:	> 95 % by SDS-PAGE
Concentration:	0.25 mg/ml (determined by Bradford assay)
Sequences of amino acids:	MGSSHHHHHH SSGLVPRGSH MGSMAQPPPD VEGDDCLPAY RHLFCPDLLR DKVAFITGGG SGIGFRIAEI FMRHGCHTVI ASRSLPRVLT AARKLAGATG RRCLPLSMDV RAPPAVMAAV DQALKEFGRI DILINCAAGN FLCPAGALSF NAFKTVMDID TSGTFNVSRV LYEKFFRDHG GVIVNITATL GNRGQALQVH AGSAKAAVDA MTRHLAVEWG PQNIRVNSLA PGPISGTEGL RRLGGPQASL STKVTASPLQ RLGNKTEIAH SVLYLASPLA SYVTGAVLVA DGGAWLTFPN GVKGLPDFAS FSAKL
Storage:	Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways:	Peroxisome; fatty acid beta-oxidation IV

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Gene Name:	DECR2 2,4-dienoyl CoA reductase 2, peroxisomal [ Homo sapiens ]
Official Symbol:	DECR2
Synonyms:	DECR2; 2,4-dienoyl CoA reductase 2, peroxisomal; PDCR; SDR17C1; peroxisomal 2,4-dienoyl-CoA reductase; OTTHUMP00000045513; OTTHUMP00000067571; 2,4-dienoyl-CoA reductase 2; short chain dehydrogenase/reductase family 17C, member 1; EC 1.3.1.34
Gene ID:	26063
mRNA Refseq:	NM_020664
Protein Refseq:	NP_065715
UniProt ID:	Q9NUI1
Chromosome Location:	16p13.3
Function:	2,4-dienoyl-CoA reductase (NADPH) activity; binding; oxidoreductase activity