"MRAS" Related Products

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Recombinant Human Muscle RAS Oncogene Homolog, His-tagged

Cat. No.: MRAS-1335H
Product Overview: Recombinant human MRAS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: MRAS (Ras-related protein M-Ras) belongs to the RAS superfamily. These families are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRAS serve as an important signal transducer for novel upstream stimuli in controlling cell proliferation.
Form: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 5 mM DTT, 40% glycerol, 200 mM NaCl, 2 mM EDTA.
Molecular Weight: 25.7 kDa (225 aa), confirmed by MALDI-TOF
Purity: > 90 % by SDS-PAGE
Concentration: 0.5 mg/ml (determined by Bradford assay)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MATSAVPSDN LPTYKLVVVG DGGVGKSALT IQFFQKIFVP DYDPTIEDSY LKHTEIDNQW AILDVLDTAG QEEFSAMREQ YMRTGDGFLI VYSVTDKASF EHVDRFHQLI LRVKDRESFP MILVANKVDL MHLRKITREQ GKEMATKHNI PYIETSAKDP PLNVDKAFHD LVRVIRQQIP EKSQKKKKKT KWRGDRATGT HKLQC
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways: HTLV-I infection; IL-3 Signaling Pathway; MAPK signaling pathway; Regulation of Actin Cytoskeleton; Tight junction
Gene Name: MRAS muscle RAS oncogene homolog [ Homo sapiens ]
Official Symbol: MRAS
Synonyms: MRAS; muscle RAS oncogene homolog; M-RAs; RRAS3; R-RAS3; FLJ42964; ras-related protein M-Ras; OTTHUMP00000216882; OTTHUMP00000216883; OTTHUMP00000216886; OTTHUMP00000216887; muscle and microspikes RAS; ras-related protein R-Ras3
Gene ID: 22808
mRNA Refseq: NM_001085049
Protein Refseq: NP_001078518
MIM: 608435
UniProt ID: O14807
Chromosome Location: 3q22.3
Function: GTP binding; GTP-dependent protein binding; GTPase activity; nucleotide binding

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