Recombinant Human GTPase Activating Protein (SH3 Domain) Binding Protein 2, His-tagged

• Cat.No.: G3BP2-4826H
• Product Overview: Recombinant human G3BP2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Cat. No.: G3BP2-4826H
• Description: G3BP2, also known as rasGTPase-activating protein-binding protein 2, is localized to the plasma membrane and endocytic compartments and controls a fast endocytic recycling pathway. This protein probably is scaffold protein that may be involved in mRNA transport.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 0.2M NaCl, 2mM DTT, 0.1mM PMSF.
• Molecular Weight: 53.3 kDa (473aa)
• Purity: >90% by SDS-PAGE
• Concentration: 1.0 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMVMEKP SPLLVGREFV RQYYTLLNKA PEYLHRFYGR NSSYVHGGVD ASGKPQEAVY GQNDIHHKVLSLNFSECHTK IRHVDAHATL SDGVVVQVMG LLSNSGQPER KFMQTFVLAP EGSVPNKFYV HNDMFRYEDE VFGDSEPELD EESEDEVEEEQEERQPSPEP VQENANSGYY EAHPVTNGIE EPLEESSHEP EPEPESETKT EELKPQVEEK NLEELEEKST TPPPAEPVSL PQEPPKPRVEAKPEVQSQPP RVREQRPRER PGFPPRGPRP GRGDMEQNDS DNRRIIRYPD SHQLFVGNLP HDIDENELKE FFMSFGNVVE LRINTKGVGGKLPNFGFVVF DDSEPVQRIL IAKPIMFRGE VRLNVEEKKT RAARERETRG GGDDRRDIRR NDRGPGGPRG IVGGGMMRDR DGRGPPPRGGMAQKLGSGRG TGQMEGRFTG QRR
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Rho GTPase cycle; Signaling by Rho GTPases; TNF-alpha/NF-kB Signaling Pathway

Gene Information

• Gene Name: G3BP2 GTPase activating protein (SH3 domain) binding protein 2 [ Homo sapiens ]
• Official Symbol: G3BP2
• Synonyms: G3BP2; GTPase activating protein (SH3 domain) binding protein 2; rasGTPase-activating protein-binding protein 2; OTTHUMP00000160586; OTTHUMP00000160587; OTTHUMP00000160588; GAP SH3 domain-binding protein 2; G3BP-2;Ras-GTPase activating protein SH3 domain-binding protein 2; OTTHUMP00000219241; KIAA0660
• Gene ID: 9908
• mRNA Refseq: NM_012297
• Protein Refseq: NP_036429
• UniProt ID: Q9UN86
• Chromosome Location: 4q21.1
• Function: RNA binding; nucleotide binding; receptor signaling complex scaffold activity