"LCMT1" Related Products

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Recombinant Human Leucine Carboxyl Methyltransferase 1, His-tagged

Cat. No.: LCMT1-1563H
Product Overview: Recombinant human LCMT7 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A.
Form: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.
Molecular Weight: 41 kDa (358aa), confirmed by MALDI-TOF.
Purity: > 95% by SDS-PAGE
Concentration: 1 mg/ml (determined by Bradford assay)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMATRQR ESSITSCCST SSCDADDEGV RGTCEDASLC KRFAVSIGYW HDPYIQHFVR LSKERKAPEI NRGYFARVHG VSQLIKAFLR KTECHCQIVN LGAGMDTTFW RLKDEDLLPS KYFEVDFPMI VTRKLHSIKC KPPLSSPILE LHSEDTLQMD GHILDSKRYA VIGADLRDLS ELEEKLKKCN MNTQLPTLLI AECVLVYMTP EQSANLLKWA ANSFERAMFI NYEQVNMGDR FGQIMIENLR RRQCDLAGVE TCKSLESQKE RLLSNGWETA SAVDMMELYN RLPRAEVSRI ESLEFLDEME LLEQLMRHYC LCWATKGGNE LGLKEITY
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways: Histidine metabolism; Tyrosine metabolism
Gene Name: LCMT1 leucine carboxyl methyltransferase 1 [ Homo sapiens ]
Official Symbol: LCMT1
Synonyms: LCMT1; leucine carboxyl methyltransferase 1; LCMT; PPMT1; CGI-68; protein-leucine O-methyltransferase; protein phosphatase methyltransferase 1; EC 2.1.1
Gene ID: 51451
mRNA Refseq: NM_001032391
Protein Refseq: NP_001027563
MIM: 610286
UniProt ID: Q9UIC8
Chromosome Location: 16p12.1
Function: S-adenosylmethionine-dependent methyltransferase activity; protein C-terminal carboxyl O-methyltransferase activity; protein binding; transferase activity

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