"PCYT2" Related Products

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Recombinant Human Phosphate Cytidylyltransferase 2, Ethanolamine, His-tagged

Cat. No.: PCYT2-1564H
Product Overview: Recombinant human PCYT2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description: PCYT2 is an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Alternative splicing results in multiple transcript variants.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT, 0.1mM PMSF.
Molecular Weight: 45.9 kDa (409aa), confirmed by MALDI-TOF.
Purity: >90% by SDS-PAGE
Concentration: 0.25 mg/ml (determined by Bradford assay)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MIRNGRGAAG GAEQPGPGGR RAVRVWCDGC YDMVHYGHSN QLRQARAMGD YLIVGVHTDE EIAKHKGPPVFTQEERYKMV QAIKWVDEVV PAAPYVTTLE TLDKYNCDFC VHGNDITLTV DGRDTYEEVK QAGRYRECKR TQGVSTTDLV GRMLLVTKAHHSSQEMSSEY REYADSFGKC PGGRNPWTGV SQFLQTSQKI IQFASGKEPQ PGETVIYVAG AFDLFHIGHV DFLEKVHRLA ERPYIIAGLHFDQEVNHYKG KNYPIMNLHE RTLSVLACRY VSEVVIGAPY AVTAELLSHF KVDLVCHGKT EIIPDRDGSD PYQEPKRRGI FRQIDSGSNLTTDLIVQRII TNRLEYEARN QKKEAKELAF LEAARQQAAQ PLGERDGDF
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways: Glycerophospholipid metabolism; Metabolic pathways; Phosphatidylethanolamine (PE) biosynthesis
Gene Name: PCYT2 phosphate cytidylyltransferase 2, ethanolamine [ Homo sapiens ]
Official Symbol: PCYT2
Synonyms: PCYT2; phosphate cytidylyltransferase 2, ethanolamine; ET; ethanolamine-phosphate cytidylyltransferase; phosphorylethanolaminetransferase; CTP:phosphoethanolaminecytidylyltransferase; EC 2.7.7.14; EC 2.7.7
Gene ID: 5833
mRNA Refseq: NM_001184917
Protein Refseq: NP_001171846
MIM: 602679
UniProt ID: Q99447
Chromosome Location: 17q25.3
Function: ethanolamine-phosphate cytidylyltransferase activity; nucleotidyltransferase activity; transferase activity

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