"SNTA1" Related Products

Recombinant Human Syntrophin, Alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component), His-tagged

Cat. No.: SNTA1-4831H
Product Overview: Recombinant human SNTA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: SNTA1 is a member of the syntrophin gene family, which is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing10% glycerol, 1mM DTT, 0.15M NaCl.
Molecular Weight: 56.3 kDa (528aa), confirmed by MALDI-TOF.
Purity: >80% by SDS-PAGE
Concentration: 1 mg/ml (determined by Bradford)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSMASGRRA PRTGLLELRA GAGSGAGGER WQRVLLSLAE DVLTVSPADG DPGPEPGAPR EQEPAQLNGA AEPGAGPPQL PEALLLQRRR VTVRKADAGG LGISIKGGRE NKMPILISKI FKGLAADQTE ALFVGDAILS VNGEDLSSAT HDEAVQVLKK TGKEVVLEVK YMKDVSPYFK NSTGGTSVGW DSPPASPLQR QPSSPGPTPR NFSEAKHMSL KMAYVSKRCT PNDPEPRYLE ICSADGQDTL FLRAKDEASA RSWATAIQAQ VNTLTPRVKD ELQALLAATS TAGSQDIKQI GWLTEQLPSG GTAPTLALLT EKELLLYLSL PETREALSRP ARTAPLIATR LVHSGPSKGS VPYDAELSFA LRTGTRHGVD THLFSVESPQ ELAAWTRQLV DGCHRAAEGV QEVSTACTWN GRPCSLSVHI DKGFTLWAAE PGAARAVLLR QPFEKLQMSS DDGASLLFLD FGGAEGEIQL DLHSCPKTIV FIIHSFLSAK VTRLGLLA
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways: Signaling mediated by p38-gamma and p38-delta
Gene Name: SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) [ Homo sapiens ]
Official Symbol: SNTA1
Synonyms: SNTA1; syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component); SNT1; LQT12; TACIP1; dJ1187J4.5; syntrophin, alpha 1 (dystrophin-associated protein A1, 59kD, acidic component); acidic alpha 1 syntrophin; alpha-1-syntrophin; Pro-TGF-alpha cytoplasmic domain-interacting protein 1; 59 kDadystrophin-associated protein A1 acidic component 1; syntrophin-1
Gene ID: 6640
mRNA Refseq: NM_003098
Protein Refseq: NP_003089
MIM: 601017
UniProt ID: Q13424
Chromosome Location: 14q11.2
Function: PDZ domain binding; actin binding; calmodulin binding; protein binding

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