Recombinant Human Tumor Necrosis Factor Receptor Superfamily, Member 11b, His-tagged
Cat.No. : | TNFRSF11B-5142H |
Product Overview : | Recombinant human osteoprotegerin protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography techniques |
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- Gene Information
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Cat. No. : | TNFRSF11B-5142H |
Description : | Osteoprotegerin (OPG) is a member of the tumor necrosis factor (TNF)-related family, is referred to as TNFRSF11B and part of the OPG/receptor activator of NF-kB ligand (RANKL)/receptor activator of NF-kB (RANK) triad. This cytokine that lacks any apparent cell-association motifs and exists as a soluble secreted protein, network regulates the differentiation and activation of osteoclasts and hence the critical balance between bone formation (osteoblasts) and bone resorption (osteoclasts). |
Concentration : | 0.5 mg/ml |
Source : | Human |
Host : | E.coli |
Form : | Supplied as a liquid in PBS, pH 7.4, containing 10% glycerol. |
Purity : | > 85 % by SDS - PAGE |
Sequence : | 22-401 amino acids: ADPETFPPKY LHYDEETSHQ LLCDKCPPGT YLKQHCTAKW KTVCAPCPDH YYTDSWHTSD ECLYCSPVCK ELQYVKQECN RTHNRVCECK EGRYLEIEFC LKHRSCPPGF GVVQAGTPER NTVCKRCPDG FFSNETSSKA PCRKHTNCSV FGLLLTQKGN ATHDNICSGN SESTQKCGID VTLCEEAFFR FAVPTKFTPN WLSVLVDNLP GTK |
Molecular Mass : | 45.6 kDa (398 aa) (On SDS-PAGE under denatured condition, apparent molecular weight of glycosylated rhOPG protein will be appeared at approximately 55 kDa) |
Applications : | SDS-PAGE |
Endotoxin Levels : | < 1.0 EU per ug of protein (determined by LAL method) |
Storage : | Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Gene Name : | TNFRSF11B tumor necrosis factor receptor superfamily, member 11b [ Homo sapiens ] |
Official Symbol : | TNFRSF11B |
Synonyms : | TNFRSF11B; OPG; OCIF; Osteoclastogenesis inhibitory factor; TR1; MGC29565; Osteoprotegerin; Osteoclastogenesis inhibitory factor; tumor necrosis factor receptor superfamily, member 11b |
Gene ID : | 4982 |
mRNA Refseq : | NM_002546 |
Protein Refseq : | NP_002537 |
MIM : | 602643 |
UniProt ID : | O00300 |
Chromosome Location : | 8q24 |
Pathway : | Cytokine-cytokine receptor interaction; Monoamine Transport; Osteoblast Signaling; Osteoclast differentiation |
Function : | Binding; cytokine activity; receptor activity |
Products Types
◆ Recombinant Protein | ||
Tnfrsf11b-310M | Recombinant Mouse TNFRSF11B Protein, Fc-His-tagged(C-ter) | +Inquiry |
TNFRSF11B-5853R | Recombinant Rat TNFRSF11B Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFRSF11B-2767H | Recombinant Human TNFRSF11B Protein, His&GST-tagged | +Inquiry |
TNFRSF11B-2768H | Recombinant Human TNFRSF11B Protein, His-tagged | +Inquiry |
TNFRSF11B-830H | Recombinant Human TNFRSF11B Protein, Fc-tagged | +Inquiry |
◆ Native Protein | ||
TNFRSF11B-54H | Native Human Osteoprotegerin | +Inquiry |
◆ Lysates | ||
TNFRSF11B-2176HCL | Recombinant Human TNFRSF11B cell lysate | +Inquiry |
TNFRSF11B-1183CCL | Recombinant Cynomolgus TNFRSF11B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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