"TNFRSF11B" Related Products

Expand
Expand

Recombinant Human Tumor Necrosis Factor Receptor Superfamily, Member 11b, His-tagged

Cat. No.: TNFRSF11B-5142H
Product Overview: Recombinant human osteoprotegerin protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography techniques
Description: Osteoprotegerin (OPG) is a member of the tumor necrosis factor (TNF)-related family, is referred to as TNFRSF11B and part of the OPG/receptor activator of NF-kB ligand (RANKL)/receptor activator of NF-kB (RANK) triad. This cytokine that lacks any apparent cell-association motifs and exists as a soluble secreted protein, network regulates the differentiation and activation of osteoclasts and hence the critical balance between bone formation (osteoblasts) and bone resorption (osteoclasts).
Concentration: 0.5 mg/ml
Source: Human
Host: E.coli
Form: Supplied as a liquid in PBS, pH 7.4, containing 10% glycerol.
Purity: > 85 % by SDS - PAGE
Sequence: 22-401 amino acids: ADPETFPPKY LHYDEETSHQ LLCDKCPPGT YLKQHCTAKW KTVCAPCPDH YYTDSWHTSD ECLYCSPVCK ELQYVKQECN RTHNRVCECK EGRYLEIEFC LKHRSCPPGF GVVQAGTPER NTVCKRCPDG FFSNETSSKA PCRKHTNCSV FGLLLTQKGN ATHDNICSGN SESTQKCGID VTLCEEAFFR FAVPTKFTPN WLSVLVDNLP GTK
Molecular Mass: 45.6 kDa (398 aa) (On SDS-PAGE under denatured condition, apparent molecular weight of glycosylated rhOPG protein will be appeared at approximately 55 kDa)
Applications: SDS-PAGE
Endotoxin Levels: < 1.0 EU per ug of protein (determined by LAL method)
Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name: TNFRSF11B tumor necrosis factor receptor superfamily, member 11b [ Homo sapiens ]
Official Symbol: TNFRSF11B
Synonyms: TNFRSF11B; OPG; OCIF; Osteoclastogenesis inhibitory factor; TR1; MGC29565; Osteoprotegerin; Osteoclastogenesis inhibitory factor; tumor necrosis factor receptor superfamily, member 11b
Gene ID: 4982
mRNA Refseq: NM_002546
Protein Refseq: NP_002537
MIM: 602643
UniProt ID: O00300
Chromosome Location: 8q24
Pathway: Cytokine-cytokine receptor interaction; Monoamine Transport; Osteoblast Signaling; Osteoclast differentiation
Function: Binding; cytokine activity; receptor activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.