Active Recombinant Human Insulin-Like Growth Factor Binding Protein 1
Cat.No. : | IGFBP1-5048H |
Product Overview : | Recombinant Human IGFBP1 was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IGFBP1-5048H |
Description : | IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity. |
Source : | Human |
Host : | E.coli |
Form : | Supplied as a lyophilized powder. |
Purity : | >97% pure by SDS PAGE and HPLC |
Sequence : | Region of IGF BP1 protein corresponding to amino acids MAPWQCAPCS AEKLALCPPV SASCSEVTRS AGCGCCPMCA LPLGAACGVA TARCARGLSC RALPGEQQPL HALTRGQGAC VQESDASAPH AAEAGSPESP ESTEITEEEL LDNFHLMAPS EEDHSILWDA ISTYDGSKAL HVTNIKKWKE PCRIELYRVV ESLAKAQETS GEEISKFYLP NC |
Molecular Mass : | 25.4 kDa |
Applications : | Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
Endotoxin Levels : | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
Bioactivity : | The ED50 was determined by its ability to inhibit IGF-I induced proliferation of MCF-7 is 0.5 ug/ml in the presence of 6 ng/ml of human IGF-I. |
Storage : | Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
Gene Name : | IGFBP1 insulin-like growth factor binding protein 1 [ Homo sapiens ] |
Official Symbol : | IGFBP1 |
Synonyms : | insulin-like AFBP; PP12; IGF-BP25; hIGFBP-1; IGFBP1; IGFBP-1; IBP-1; IGF-binding protein 1; insulin-like growth factor binding protein 1; binding protein-25; binding protein-26; binding protein-28; placental protein 12; IGF-binding protein 1; amniotic fluid binding protein; growth hormone independent-binding protein; alpha-pregnancy-associated endometrial globulin; OTTHUMP00000159561; OTTHUMP00000207990; OTTHUMP00000214348 |
Gene ID : | 3484 |
mRNA Refseq : | NM_000596 |
Protein Refseq : | NP_000587 |
MIM : | 146730 |
UniProt ID : | P08833 |
Chromosome Location : | 7p13-p12 |
Pathway : | Diabetes pathways; FOXA2 and FOXA3 transcription factor networks; HIF-1-alpha transcription factor network; Myometrial Relaxation and Contraction Pathways; PERK regulated gene expression; Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs); Unfolded Protein Response |
Function : | insulin-like growth factor binding |
Products Types
◆ Recombinant Protein | ||
Igfbp1-10568M | Recombinant Mouse Igfbp1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGFBP1-300R | Recombinant Rhesus macaque IGFBP1 Protein, His-tagged | +Inquiry |
IGFBP1-1387H | Recombinant Human IGFBP1 Protein, MYC/DDK-tagged | +Inquiry |
IGFBP1-0013H | Recombinant Human IGFBP1 Protein | +Inquiry |
IGFBP1-2663R | Recombinant Rat IGFBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
IGFBP1-612H | Native Human Insulin-like Growth Factor Binding Protein 1 | +Inquiry |
◆ Lysates | ||
IGFBP1-1482CCL | Recombinant Cynomolgus IGFBP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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