"CXCL1" Related Products

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Recombinant Human Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha)

Cat. No.: CXCL1-334H
Product Overview: Recombinant Human GRO/KC is a 7.8 kDa protein consisting of 72 amino acids including the "ELR" motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
Description: All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils
Source: Human
Host: E.coli
Form: Supplied as a lyophilized powder.
Purity: >98% pure by SDS PAGE and HPLC
Sequence: Region of GRO protein corresponding to amino acids APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK.
Molecular Mass: 7.8 kDa
Applications: Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions
Endotoxin Levels: Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Bioactivity: Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml.
Storage: Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name: CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) [ Homo sapiens ]
Official Symbol: CXCL1
Synonyms: CXCL1; FSP; GRO; GRO1; GROA; GROa; MGSA; MGSA-a; NAP-3; SCYB1; MGSA alpha; C-X-C motif chemokine 1; GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); Melanoma growth stimulatory activity; Neutrophil-activating protein 3; chemokine (C-X-C motif) ligand 1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); fibroblast secretory protein; melanoma growth stimulatory activity alpha; GROA_HUMAN; Growth-regulated alpha protein [Precursor]; GRO-alpha(1-73)
Gene ID: 2919
mRNA Refseq: NM_001511
Protein Refseq: NP_001502
MIM: 155730
UniProt ID: P09341
Chromosome Location: 4q21
Pathway: Amoebiasis; Chemokine receptors bind chemokines; Class A/1 (Rhodopsin-like receptors); Cytokine-cytokine receptor interaction; Cytokines and Inflammatory Response; Epithelial cell signaling in Helicobacter pylori infection; G alpha (i) signalling events; GPCR downstream signaling; GPCR ligand binding; IL23-mediated signaling events; Legionellosis; NOD-like receptor signaling pathway; Peptide ligand-binding receptors; Rheumatoid arthritis; Salmonella infection; Senescence and Autophagy; Signaling by GPCR
Function: chemokine activity; enzyme activator activity; growth factor activity; receptor binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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