Active Recombinant Human Defensin, Beta 4A
| Cat.No. : | DEFB4A-037H |
| Product Overview : | Recombinant human protein was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
| Cat. No. : | DEFB4A-037H |
| Description : | Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, four human beta-defensins have been identified; BD-1, BD-2, BD-3 and BD-4. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. |
| Source : | Human |
| Host : | E.coli |
| Form : | Supplied lyophilized with no additives. Reconstitute in 10 mM Acetic Acid to a concentration of 0.1 - 1.0 mg/ml. |
| Purity : | >98% pure by SDS PAGE and HPLC |
| Sequence : | Region of BD2 protein corresponding to amino acids GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P. |
| Molecular Mass : | 4.3 kDa |
| Applications : | Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
| Endotoxin Levels : | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
| Bioactivity : | Determined by its ability to chemoattract immature human dendritic cells using a concentration of 10.0-100.0 ng/ml. |
| Storage : | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
| Gene Name : | DEFB4A defensin, beta 4A [ Homo sapiens ] |
| Official Symbol : | DEFB4A |
| Synonyms : | DEFB4A; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB102; BD-2; DEFB4B; hBD-2; defensin, beta 4A; beta-defensin 4A; defensin, beta 2; defensin, beta 4; OTTHUMP00000159651; skin-antimicrobial peptide 1; Beta-defensin 2 |
| Gene ID : | 1673 |
| mRNA Refseq : | NM_004942 |
| Protein Refseq : | NP_004933 |
| MIM : | 602215 |
| UniProt ID : | O15263 |
| Chromosome Location : | 8p23.1 |
Products Types
| ◆ Recombinant Protein | ||
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| DEFB4A-1064R | Recombinant Rhesus Macaque DEFB4A Protein, His (Fc)-Avi-tagged | +Inquiry |
| DEFB4A-5133H | Recombinant Human DEFB4A Protein, GST-tagged | +Inquiry |
| DEFB4A -5387H | Recombinant Human Defensin, Beta 4A | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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