"FGF23" Related Products

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Recombinant Human Fibroblast Growth Factor 23

Cat. No. : FGF23-618H
Product Overview : Recombinant human FGF23 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Description : The FGF family plays a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF23, FGF21 and FGF19 constitute an atypical FGF subfamily whose ligands act as circulating hormones and require the participation of a Klotho protein as a co-receptor for their signaling. FGF23 is a bone-derived hormone that acts in the kidney to regulate phosphate homeostasis and vitamin D metabolism. The signaling receptor for FGF23, a Klotho-FGFR1 (IIIc) complex, is an essential regulator of the renal sodium phosphate co-transporter and key vitamin D-metabolizing enzymes CYP27B1 and CYP24A1.
Source : Human
Host : E.coli
Form : Supplied as a lyophilized powder.
Purity : > 95% by SDS - PAGE
Sequence : Region of FGF23 protein corresponding to amino acids MYPNASPLLG SSWGGLIHLY TATARNSYHL QIHKNGHVDG APHQTIYSAL MIRSEDAGFV VITGVMSRRY LCMDFRGNIF GSHYFDPENC RFQHQTLENG YDVYHSPQYH FLVSLGRAKR AFLPGMNPPP YSQFLSRRNE IPLIHFNTPI PRRHTRSAED DSERDPLNVL KPRARMTPAP ASCS
Molecular Mass : 22.5 kDa
Applications : Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions.
Endotoxin Levels : Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Storage : Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name : FGF23 fibroblast growth factor 23 [ Homo sapiens ]
Official Symbol : FGF23
Synonyms : FGF23; fibroblast growth factor 23; ADHR; HYPF; HPDR2; PHPTC; FGF-23; Phosphatonin; UNQ3027/PRO9828; Fibroblast growth factor 23 N-terminal peptide; Fibroblast growth factor 23 C-terminal peptide; tumor-derived hypophosphatemia inducing factor; Tumor-derived hypophosphatemia-inducing factor
Gene ID : 8074
mRNA Refseq : NM_020638
Protein Refseq : NP_065689
MIM : 605380
UniProt ID : Q9GZV9
Chromosome Location : 12p13.3
Pathway : MAPK signaling pathway; Melanoma; Pathways in cancer; Regulation of actin cytoskeleton; Signaling by FGFR
Function : growth factor activity

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