"HDAC2" Related Products

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Recombinant Human Histone Deacetylase 2, His-tagged

Cat. No.: HDAC2-1699H
Product Overview: Recombinant human HDAC2 protein was expressed with c-terminal His-tag in high-5 cells using baculovirus expression system and purified by using conventional chromatography techniques.
Description: HDAC2 belongs to the histone deacetylase family that act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues on the N-terminal region of the core histones. It forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. It also plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Concentration: 0.25 mg/ml
Source: Human
Host: Hi-5 cells
Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol, 0.1M NaCl, 1mM DTT and 0.1mM PMSF.
Purity: > 85% by SDS - PAGE
Sequence: 1-488 amino acids: MAYSQGGGKK KVCYYYDGDI GNYYYGQGHP MKPHRIRMTH NLLLNYGLYR KMEIYRPHKA TAEEMTKYHS DEYIKFLRSI RPDNMSEYSK QMQRFNVGED CPVFDGLFEF CQLSTGGSVA GAVKLNRQQT DMAVNWAGGL HHAKKSEASG FCYVNDIVLA ILELLKYHQR VLYIDIDIHH GDGVEEAFYT TDRVMTVSFH KYGEYFPGTG DLRDI
Molecular Mass: 56.4 kDa (496aa)
Applications: SDS-PAGE
Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name: HDAC2 histone deacetylase 2 [ Homo sapiens ]
Official Symbol: HDAC2
Synonyms: HDAC2; RPD3; YAF1; histone deacetylase 2; OTTHUMP00000040427; YY1-associated factor 1; transcriptional regulator homolog RPD3; EC 3.5.1.98; HD2
Gene ID: 3066
mRNA Refseq: NM_001527
Protein Refseq: NP_001518
MIM: 605164
UniProt ID: Q92769
Chromosome Location: 6q21
Pathway: Cell cycle; Chronic myeloid leukemia; Notch signaling pathway; Gene Expression; Signalling by NGF
Function: enzyme binding; histone deacetylase activity; hydrolase activity; specific transcriptional repressor activity; transcription activator activity; transcription factor activity; transcription factor binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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