"HSD17B10" Related Products

Expand
Expand

Recombinant Human Hydroxysteroid Dehydrogenase 10, His-tagged

Cat. No.: HSD17B10-1707H
Product Overview: Recombinant HSD17B10 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Description: HSD17B10 is a member of the short-chain dehydrogenase/reductase superfamily. This mitochondrial protein catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. HSD17B10 plays an important role in processing steroid hormones and fats, and also helps break down the protein building block (amino acid) isoleucine. This enzyme is also necessary for several chemical reactions involving female sex hormones (estrogens) and male sex hormones (androgens). It is essential for maintaining appropriate levels of male and female sex hormones. This protein may contribute to the neuronal dysfunction associated with Alzheimer disease.
Concentration: 1 mg/ml
Source: Human
Host: E.coli
Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 1mM DTT, and 100mM NaCl.
Purity: > 95% by SDS - PAGE
Sequence: 12-261 amino acids: MGSSHHHHHH SSGLVPRGSH MVAVITGGAS GLGLATAERL VGQGASAVLL DLPNSGGEAQ AKKLGNNCVF APADVTSEKD VQTALALAKG KFGRVDVAVN CAGIAVASKT YNLKKGQTHT LEDFQRVLDV NLMGTFNVIR LVAGEMGQNE PDQGGQRGVI INTASVAAFE GQVGQAAYSA SKGGIVGMTL PIARDLAPIG IRVMTIAPGL FGTP
Molecular Mass: 28.1 kDa (271aa), confirmed by MALDI-TOF.
Applications: SDS-PAGE
Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name: HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 [ Homo sapiens]
Official Symbol: HSD17B10
Synonyms: HSD17B10; hydroxysteroid (17-beta) dehydrogenase 10; ABAD; CAMR; ERAB; HCD2; MHBD; HADH2; MRPP2; MRX17; MRX31; SCHAD; MRXS10; SDR5C1; 17b-HSD10; DUPXp11.22; AB-binding alcohol dehydrogenase; amyloid-beta binding polypeptide; mental retardation, X-linked, syndromic 10; mental retardation, X-linked, syndromic 11; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; type 10 17beta-hydroxysteroid dehydrogenase; 17-beta-hydroxysteroid dehydrogenase type 10; short chain type dehydrogenase/reductase XH98G2; amyloid-beta peptide binding alcohol dehydrogenase; short chain L-3-hydroxyacyl-CoA dehydrogenase type 2; short chain dehydrogenase/reductase family 5C, member 1; EC 1.1.1.178; EC 1.1.1.35; hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme A dehydrogenase, type II; type 10 17b-HSD; short chain dehydrogenase/reductase family 5C, member 1; 3-hydroxyacyl-CoA dehydrogenase type-2; 3-hydroxyacyl-CoA dehydrogenase type II; Type II HADH; 17-beta-hydroxysteroid dehydrogenase 10; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; XH98G2; OTTHUMP00000023348; OTTHUMP00000023349
Gene ID: 3028
mRNA Refseq: NM_001037811
Protein Refseq: NP_001032900
MIM: 300256
UniProt ID: Q99714
Chromosome Location: Xp11.2
Pathway: Alzheimer"s disease; Metabolic pathways; Valine, leucine and isoleucine degradation
Function: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; 3-hydroxyacyl-CoA dehydrogenase activity; 7-alpha-hydroxysteroid dehydrogenase activity; NAD or NADH binding; acetoacetyl-CoA reductase activity; beta-amyloid binding; estradiol 17-beta-dehydrogenase activity; identical protein binding; oxidoreductase activity; steroid binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.