"IL15" Related Products

Expand
Expand
Expand

Recombinant Human Interleukin 15, His-tagged

Cat. No.: IL15-532H
Product Overview: Recombinant human IL-15 was expressed in E. coli and purified by using conventional chromatography after refolding of the isolated inclusion bodies in a redox buffer.
Description: Interleukin (IL-15) is a pleiotropic cytokine that plays a pivotal role in both innate and adaptive immunity. IL-15 is unique among cytokines due to its participation in a trans signaling mechanism in which IL-15 receptor alpha (IL-15R alpha) from one subset of cells presents IL-15 to neighboring IL-2R beta/gamma(c)-expressing cells. This newly discovered cytokine is produced by a wide variety of cells and tissues and like IL-2, stimulates the proliferation of T-lymphocytes and induces the generation of cytotoxic T-lymphocytes (CTLs) and lymphokine-activated killer (LAK) cells.
Concentration: 1 mg/ml
Source: Human
Host: E.coli
Form: Supplied as a liquid in PNS, pH 7.4, containing 0.2mM PMSF, and 10% glycerol.
Purity: > 95% by SDS - PAGE
Sequence: 20-152 amino acids: MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTSLEHHH HHH
Molecular Mass: 13.9 kDa (123aa), confirmed by MALDI-TOF.
Applications: SDS-PAGE
Bioactivity: The ED50 for this effect is < 2.5 ng/ml. Measured in a cell proliferation assay using CTLL2 mouse cytotoxic T cells.
Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name: IL15 interleukin 15 [ Homo sapiens ]
Official Symbol: IL15
Synonyms: IL15; interleukin 15; IL-15; MGC9721; OTTHUMP00000164617
Gene ID: 3600
mRNA Refseq: NM_000585
Protein Refseq: NP_000576
MIM: 600554
UniProt ID: P40933
Chromosome Location: 4q31
Pathway: Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function: cytokine activity; cytokine receptor binding; protein binding; signal transducer activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.